SGSH antibody (AA 273-502)

Catalog No. ABIN6147711

Product Details anti-SGSH Antibody

Target: SGSH (N-Sulfoglucosamine Sulfohydrolase (SGSH))

Binding Specificity: AA 273-502

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SGSH antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: DNGIPFPSGR TNLYWPGTAE PLLVSSPEHP KRWGQVSEAY VSLLDLTPTI LDWFSIPYPS YAIFGSKTIH LTGRSLLPAL EAEPLWATVF GSQSHHEVTM SYPMRSVQHR HFRLVHNLNF KMPFPIDQDF YVSPTFQDLL NRTTAGQPTG WYKDLRHYYY RARWELYDRS RDPHETQNLA TDPRFAQLLE MLRDQLAKWQ WETHDPWVCA PDGVLEEKLS PQCQPLHNEL

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 273-502 of human SGSH (NP_000190.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Comment:

HIGH QUALITY

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for SGSH

Target: SGSH (N-Sulfoglucosamine Sulfohydrolase (SGSH))

Alternative Name: SGSH (SGSH Products)

Synonyms: HSS antibody, MPS3A antibody, SFMD antibody, 4632406A19Rik antibody, N-sulfoglucosamine sulfohydrolase antibody, N-sulfoglucosamine sulfohydrolase (sulfamidase) antibody, SGSH antibody, Sgsh antibody

Background: This gene encodes one of several enzymes involved in the lysosomal degradation of heparan sulfate. Mutations in this gene are associated with Sanfilippo syndrome A, one type of the lysosomal storage disease mucopolysaccaridosis III, which results from impaired degradation of heparan sulfate. Transcripts of varying sizes have been reported but their biological validity has not been determined.,SGSH,HSS,MPS3A,SFMD,Signal Transduction,Cell Biology & Developmental Biology,Cytoskeleton,Neuroscience,Neurodegenerative Diseases,SGSH

Molecular Weight: 56 kDa

Gene ID: 6448

UniProt: P51688

Pathways: Glycosaminoglycan Metabolic Process