SMAD5 antibody (AA 186-465)

Catalog No. ABIN6148090

This anti-SMAD5 antibody is a Rabbit Polyclonal antibody detecting SMAD5 in WB, IHC and IF. Suitable for Human.

Quick Overview for SMAD5 antibody (AA 186-465) (ABIN6148090)

Target: SMAD5 (SMAD, Mothers Against DPP Homolog 5 (SMAD5))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SMAD5 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-SMAD5 Antibody

Binding Specificity: AA 186-465

Sequence: PLSPNSPYPP SPASSTYPNS PASSGPGSPF QLPADTPPPA YMPPDDQMGQ DNSQPMDTSN NMIPQIMPSI SSRDVQPVAY EEPKHWCSIV YYELNNRVGE AFHASSTSVL VDGFTDPSNN KSRFCLGLLS NVNRNSTIEN TRRHIGKGVH LYYVGGEVYA ECLSDSSIFV QSRNCNFHHG FHPTTVCKIP SSCSLKIFNN QEFAQLLAQS VNHGFEAVYE LTKMCTIRMS FVKGWGAEYH RQDVTSTPCW IEIHLHGPLQ WLDKVLTQMG SPLNPISSVS

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 186-465 of human Smad5 (NP_001001420.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for SMAD5

Target: SMAD5 (SMAD, Mothers Against DPP Homolog 5 (SMAD5))

Alternative Name: Smad5

Background: The protein encoded by this gene is involved in the transforming growth factor beta signaling pathway that results in an inhibition of the proliferation of hematopoietic progenitor cells. The encoded protein is activated by bone morphogenetic proteins type 1 receptor kinase, and may be involved in cancer. Alternative splicing results in multiple transcript variants.,DWFC,JV5-1,MADH5,SMAD5,Epigenetics & Nuclear Signaling,Signal Transduction,Cell Biology & Developmental Biology,TGF-b-Smad Signaling Pathway,ESC Pluripotency and Differentiation,Stem Cells,SMADs,Smad5

Molecular Weight: 52 kDa

Gene ID: 4090

UniProt: Q99717