SMOX antibody (AA 1-200)

Catalog No. ABIN6148142

The Rabbit Polyclonal anti-SMOX antibody has been validated for WB and IHC. It is suitable to detect SMOX in samples from Human.

Quick Overview for SMOX antibody (AA 1-200) (ABIN6148142)

Target: SMOX (Spermine Oxidase (SMOX))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SMOX antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-SMOX Antibody

Binding Specificity: AA 1-200

Sequence: MQSCESSGDS ADDPLSRGLR RRGQPRVVVI GAGLAGLAAA KALLEQGFTD VTVLEASSHI GGRVQSVKLG HATFELGATW IHGSHGNPIY HLAEANGLLE ETTDGERSVG RISLYSKNGV ACYLTNHGRR IPKDVVEEFS DLYNEVYNLT QEFFRHDKPV NAESQNSVGV FTREEVRNRI RNDPDDPEAT KRLKLAMIQQ

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-200 of human SMOX (NP_787034.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IHC,1:50 - 1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for SMOX

Target: SMOX (Spermine Oxidase (SMOX))

Alternative Name: SMOX

Background: Polyamines are ubiquitous polycationic alkylamines which include spermine, spermidine, putrescine, and agmatine. These molecules participate in a broad range of cellular functions which include cell cycle modulation, scavenging reactive oxygen species, and the control of gene expression. These molecules also play important roles in neurotransmission through their regulation of cell-surface receptor activity, involvement in intracellular signalling pathways, and their putative roles as neurotransmitters. This gene encodes an FAD-containing enzyme that catalyzes the oxidation of spermine to spermadine and secondarily produces hydrogen peroxide. Multiple transcript variants encoding different isoenzymes have been identified for this gene, some of which have failed to demonstrate significant oxidase activity on natural polyamine substrates. The characterized isoenzymes have distinctive biochemical characteristics and substrate specificities, suggesting the existence of additional levels of complexity in polyamine catabolism.,SMOX,C20orf16,PAO,PAO-1,PAO1,PAOH,PAOH1,SMO,Signal Transduction,Endocrine & Metabolism,Amino acid metabolism,Drug metabolism,SMOX

Molecular Weight: 20 kDa/43 kDa/56 kDa/59 kDa/61 kDa/65 kDa

Gene ID: 54498

UniProt: Q9NWM0