SMOX antibody (Internal Region)

Catalog No. ABIN6265191

Product Details anti-SMOX Antibody

Target: SMOX (Spermine Oxidase (SMOX))

Binding Specificity: Internal Region

Reactivity: Mouse, Human, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SMOX antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunofluorescence (IF)

Specificity: SMOX Antibody detects endogenous levels of total SMOX.

Predicted Reactivity: Pig,Bovine,Horse,Sheep,Rabbit,Dog,Chicken,Xenopus

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human SMOX, corresponding to a region within the internal amino acids.

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C. Stable for 12 months from date of receipt.

Expiry Date: 12 months

Target Details for SMOX

Target: SMOX (Spermine Oxidase (SMOX))

Alternative Name: SMOX (SMOX Products)

Synonyms: cb1027 antibody, wu:fq32f10 antibody, zgc:77167 antibody, MGC81392 antibody, APAO antibody, ATPAO1 antibody, MSH12.17 antibody, MSH12_17 antibody, polyamine oxidase 1 antibody, C20orf16 antibody, PAO antibody, PAO-1 antibody, PAOH1 antibody, SMO antibody, B130066H01Rik antibody, PAOh1 antibody, spermine oxidase antibody, spermine oxidase S homeolog antibody, polyamine oxidase 1 antibody, smox antibody, SMOX antibody, smox.S antibody, PAO1 antibody, Smox antibody

Background:

Description: Flavoenzyme which catalyzes the oxidation of spermine to spermidine. Can also use N1-acetylspermine and spermidine as substrates, with different affinity depending on the isoform (isozyme) and on the experimental conditions. Plays an important role in the regulation of polyamine intracellular concentration and has the potential to act as a determinant of cellular sensitivity to the antitumor polyamine analogs. May contribute to beta-alanine production via aldehyde dehydrogenase conversion of 3-amino-propanal.

Gene: SMOX

Molecular Weight: 62 kDa

Gene ID: 54498

UniProt: Q9NWM0