beta Amyloid antibody (C-Term)

Catalog No. ABIN614817

This anti-beta Amyloid antibody is a Mouse Monoclonal antibody detecting beta Amyloid in EIA and ELISA (Detection). Suitable for Human.

Quick Overview for beta Amyloid antibody (C-Term) (ABIN614817)

Target: beta Amyloid (Abeta) (Amyloid beta (Abeta))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This beta Amyloid antibody is un-conjugated

Application: Enzyme Immunoassay (EIA), ELISA (Detection)

Clone: CV9 7B10

Product Details anti-beta Amyloid Antibody

Binding Specificity: C-Term

Sequence: GLMVGGVV

Specificity: This antibody recognizes the C-terminal peptide of beta amyloid peptide 40, and full length beta amyloid peptide 40.

Cross-Reactivity (Details): Species reactivity (tested):Human.

Purification: Protein G affinity chromatography

Immunogen: C-terminal amino acid sequence of human beta amyloid peptide 40, conjugated with KLH

Isotype: IgG1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Reconstitution: Restore with Double distillated water is recommended to adjust the final concentration to 1.0 mg/mL.

Buffer: 0.01 M PBS pH 7.2

Handling Advice: Avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store (in aliquots) at -20 °C.

Target Details for beta Amyloid

Target: beta Amyloid (Abeta) (Amyloid beta (Abeta))

Alternative Name: Amyloid beta

Background: Aβ40, Aβ42 and Aβ43 are different only at the few C-end amino acids. While the C-end amino acids showed no speciesspecificity in mammalians, the Nterminal amino acid sequences have minor discrepancies between difference species. Amyloid beta peptides Aβ42 and Aβ40 have been investigated extensively for predicating Alzheimer's disease. A recent study on A Aβ43 in brain showed that Aβ43 is more fibrillogenic than the other amyloid beta peptides and may be useful as a biomarker or therapeutic target for Alzheimer's disease. Antibody to N-terminal sequence can bind to all the three amyloid beta peptides.

Gene ID: 351

Pathways: Inflammasome