SNX15 antibody (AA 1-342)

Catalog No. ABIN6148238

The Rabbit Polyclonal anti-SNX15 antibody (ABIN6148238) specifically detects SNX15 in WB and IF. The antibody is reactive with Human samples.

Quick Overview for SNX15 antibody (AA 1-342) (ABIN6148238)

Target: SNX15 (Sorting Nexin 15 (SNX15))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SNX15 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF)

Product Details anti-SNX15 Antibody

Binding Specificity: AA 1-342

Sequence: MSRQAKDDFL RHYTVSDPRT HPKGYTEYKV TAQFISKKDP EDVKEVVVWK RYSDFRKLHG DLAYTHRNLF RRLEEFPAFP RAQVFGRFEA SVIEERRKGA EDLLRFTVHI PALNNSPQLK EFFRGGEVTR PLEVSRDLHI LPPPLIPTPP PDDPRLSQLL PAERRGLEEL EVPVDPPPSS PAQEALDLLF NCESTEEASG SPARGPLTEA ELALFDPFSK EEGAAPSPTH VAELATMEVE SARLDQEPWE PGGQEEEEDG EGGPTPAYLS QATELITQAL RDEKAGAYAA ALQGYRDGVH VLLQGVPSDP LPARQEGVKK KAAEYLKRAE EILRLHLSQL PP

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-342 of human SNX15 (NP_037438.2).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IF,1:50 - 1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for SNX15

Target: SNX15 (Sorting Nexin 15 (SNX15))

Alternative Name: SNX15

Background: This gene encodes a member of the sorting nexin family. Members of this family contain a phox (PX) domain, which is a phosphoinositide binding domain, and are involved in intracellular trafficking. Overexpression of this gene results in a decrease in the processing of insulin and hepatocyte growth factor receptors to their mature subunits. This decrease is caused by the mislocalization of furin, the endoprotease responsible for cleavage of insulin and hepatocyte growth factor receptors. This protein is involved in endosomal trafficking from the plasma membrane to recycling endosomes or the trans-Golgi network. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the upstream ADP-ribosylation factor-like 2 (ARL2) gene.,SNX15,HSAF001435,Signal Transduction,SNX15

Molecular Weight: 29 kDa/38 kDa

Gene ID: 29907

UniProt: Q9NRS6