CD43 antibody (AA 276-400)

Catalog No. ABIN6148363

This Rabbit Polyclonal antibody specifically detects CD43 in WB, IHC and IF. It exhibits reactivity toward Human.

Quick Overview for CD43 antibody (AA 276-400) (ABIN6148363)

Target: CD43 (SPN) (Sialophorin (SPN))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CD43 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-CD43 Antibody

Binding Specificity: AA 276-400

Sequence: LWRRRQKRRT GALVLSRGGK RNGVVDAWAG PAQVPEEGAV TVTVGGSGGD KGSGFPDGEG SSRRPTLTTF FGRRKSRQGS LAMEELKSGS GPSLKGEEEP LVASEDGAVD APAPDEPEGG DGAAP

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 276-400 of human SPN (NP_003114.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200

Comment:

HIGH QUALITY

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for CD43

Target: CD43 (SPN) (Sialophorin (SPN))

Alternative Name: SPN

Background: The protein encoded by this gene is a major sialoglycoprotein found on the surface of thymocytes, T lymphocytes, monocytes, granulocytes, and some B lymphocytes. It may be part of a physiologic ligand-receptor complex involved in T-cell activation. During T-cell activation, this protein is actively removed from the T-cell-APC (antigen-presenting cell) contact site, suggesting a negative regulatory role in adaptive immune response.,SPN,CD43,GALGP,GPL115,LSN,Cell Biology & Developmental Biology,Apoptosis,Immunology & Inflammation,CD markers,Stem Cells,Hematopoietic Progenitors,SPN

Molecular Weight: 40 kDa

Gene ID: 6693

UniProt: P16150

Pathways: Regulation of Leukocyte Mediated Immunity