SULF1 antibody (AA 400-700)

Catalog No. ABIN6148697

The Rabbit Polyclonal anti-SULF1 antibody (ABIN6148697) specifically detects SULF1 in WB. The antibody is reactive with Human samples.

Quick Overview for SULF1 antibody (AA 400-700) (ABIN6148697)

Target: SULF1 (Sulfatase 1 (SULF1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SULF1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-SULF1 Antibody

Binding Specificity: AA 400-700

Sequence: TNKKAKIWRD TFLVERGKFL RKKEESSKNI QQSNHLPKYE RVKELCQQAR YQTACEQPGQ KWQCIEDTSG KLRIHKCKGP SDLLTVRQST RNLYARGFHD KDKECSCRES GYRASRSQRK SQRQFLRNQG TPKYKPRFVH TRQTRSLSVE FEGEIYDINL EEEEELQVLQ PRNIAKRHDE GHKGPRDLQA SSGGNRGRML ADSSNAVGPP TTVRVTHKCF ILPNDSIHCE RELYQSARAW KDHKAYIDKE IEALQDKIKN LREVRGHLKR RKPEECSCSK QSYYNKEKGV KKQEKLKSHL H

Cross-Reactivity: Human, Rat

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 400-700 of human SULF1 (NP_055985.2).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for SULF1

Target: SULF1 (Sulfatase 1 (SULF1))

Alternative Name: SULF1

Background: This gene encodes an extracellular heparan sulfate endosulfatase. The encoded enzyme selectively removes 6-O-sulfate groups from heparan sulfate chains of heparan sulfate proteoglycans (HSPGs). The enzyme is secreted through the Golgi and is subsequently localized to the cell surface. The expression of this gene may be down-regulated in several types of cancer, including hepatocellular (HCC), ovarian and breast cancers. Alternative splicing results in multiple transcript variants.,SULF1,SULF-1,Cancer,Invasion and Metastasis,Signal Transduction,Cell Biology & Developmental Biology,Apoptosis,Cytoskeleton,SULF1

Molecular Weight: 101 kDa

Gene ID: 23213

UniProt: Q8IWU6

Pathways: EGFR Signaling Pathway