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APOH antibody
APOH
Reactivity: Human, Rat, Dog, Pig, Rabbit
IHC (p), EIA
Host: Goat
Polyclonal
unconjugated
Product Details anti-APOH Antibody
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Target
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APOH
(Apolipoprotein H (Beta-2-Glycoprotein I) (APOH))
Reactivity
All reactivities for APOH antibodies
Human, Rat, Dog, Pig, Rabbit
Host
All hosts for APOH antibodies
Goat
Clonality
All clonalities for APOH antibodies
Polyclonal
Conjugate
All conjugates for APOH antibodies
This APOH antibody is un-conjugated
Application
All applications for APOH antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
Specificity
This antibody recognizes beta2GP-I. A single precipitin arc is observed with normal plasma. No arc was seen with beta2GP-I deficient plasma.
Cross-Reactivity (Details)
Species reactivity (tested):Human, mouse, porcine, rat, rabbit, canine
Purification
Immunoaffinity chromatography
Immunogen
Human beta2-Glycoprotein-I (beta2GP-I) purified from plasma Genename: APOH
Isotype
IgG
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Alternatives
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Application Details
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Application Notes
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Handling
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Concentration
2.0 mg/mL
Buffer
10 mM HEPES, pH 7.4, 0.15 M sodium chloride, 50 % glycerol
Handling Advice
Avoid repeated freezing and thawing.
Storage
4 °C/-20 °C
Storage Comment
Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
Target Details for APOH
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Target
APOH
(Apolipoprotein H (Beta-2-Glycoprotein I) (APOH))
Alternative Name
Apolipoprotein H (Apo H) (APOH Products )
Synonyms
B2G1 antibody, B2GP1 antibody, BG antibody, BETA2 antibody, BHF-1 antibody, MODY6 antibody, NEUROD antibody, bHLHa3 antibody, apoh antibody, APOH antibody, B2GPI antibody, beta-2-GPI antibody, beta2-GPI antibody, LOC100227913 antibody, apolipoprotein H antibody, neuronal differentiation 1 antibody, APOH antibody, NEUROD1 antibody, apoh antibody, Apoh antibody
Background
Apolipoprotein H has been implicated in a variety of physiologic pathways including lipoprotein metabolism, coagulation, and the production of antiphospholipid autoantibodies. APOH may be a required cofactor for anionic phospholipid binding by the antiphospholipid autoantibodies found in sera of many patients with lupus and primary antiphospholipid syndrome, but it does not seem to be required for the reactivity of antiphospholipid autoantibodies associated with infections.Synonyms: APC Inhibitor, Anticardiolipin Cofactor, Apo-H, ApoH, B2G1, B2GPI, Beta-2-glycoprotein I, Beta2GPI
Gene ID
350
NCBI Accession
NP_000033
UniProt
P02749
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