TBXAS1 antibody (AA 355-534)

Catalog No. ABIN6148915

This Rabbit Polyclonal antibody specifically detects TBXAS1 in WB and IHC. It exhibits reactivity toward Human.

Quick Overview for TBXAS1 antibody (AA 355-534) (ABIN6148915)

Target: TBXAS1 (thromboxane A Synthase 1 (Platelet) (TBXAS1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TBXAS1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-TBXAS1 Antibody

Binding Specificity: AA 355-534

Sequence: TYLLATNPDC QEKLLREVDV FKEKHMAPEF CSLEEGLPYL DMVIAETLRM YPPAFRFTRE AAQDCEVLGQ RIPAGAVLEM AVGALHHDPE HWPSPETFNP ERFTAEARQQ HRPFTYLPFG AGPRSCLGVR LGLLEVKLTL LHVLHKFRFQ ACPETQVPLQ LESKSALGPK NGVYIKIVSR

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 355-534 of human Thromboxane synthase (NP_001052.2).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IHC,1:50 - 1:200

Comment:

HIGH QUALITY

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for TBXAS1

Target: TBXAS1 (thromboxane A Synthase 1 (Platelet) (TBXAS1))

Alternative Name: TBXAS1

Background: This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. However, this protein is considered a member of the cytochrome P450 superfamily on the basis of sequence similarity rather than functional similarity. This endoplasmic reticulum membrane protein catalyzes the conversion of prostglandin H2 to thromboxane A2, a potent vasoconstrictor and inducer of platelet aggregation. The enzyme plays a role in several pathophysiological processes including hemostasis, cardiovascular disease, and stroke. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.,TBXAS1,BDPLT14,CYP5,CYP5A1,GHOSAL,THAS,TS,TXAS,TXS,Cancer,Signal Transduction,Cell Biology & Developmental Biology,Endocrine & Metabolism,Cardiovascular,Heart,Cardiovascular diseases,Heart disease,TBXAS1

Molecular Weight: 52 kDa/60 kDa/65 kDa

Gene ID: 6916

UniProt: P24557