THRA antibody (AA 100-200)

Catalog No. ABIN6149127

The Rabbit Polyclonal anti-THRA antibody has been validated for WB and IHC. It is suitable to detect THRA in samples from Human.

Quick Overview for THRA antibody (AA 100-200) (ABIN6149127)

Target: THRA (Thyroid Hormone Receptor, alpha (THRA))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This THRA antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-THRA Antibody

Binding Specificity: AA 100-200

Sequence: DKITRNQCQL CRFKKCIAVG MAMDLVLDDS KRVAKRKLIE QNRERRRKEE MIRSLQQRPE PTPEEWDLIH IATEAHRSTN AQGSHWKQRR KFLPDDIGQS P

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Immunogen: A synthetic peptide corresponding to a sequence within amino acids 100-200 of human THRA (NP_003241.2).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IHC,1:50 - 1:200

Comment:

HIGH QUALITY

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for THRA

Target: THRA (Thyroid Hormone Receptor, alpha (THRA))

Alternative Name: THRA

Background: The protein encoded by this gene is a nuclear hormone receptor for triiodothyronine. It is one of the several receptors for thyroid hormone, and has been shown to mediate the biological activities of thyroid hormone. Knockout studies in mice suggest that the different receptors, while having certain extent of redundancy, may mediate different functions of thyroid hormone. Alternatively spliced transcript variants encoding distinct isoforms have been reported.,THRA,AR7,CHNG6,EAR7,ERB-T-1,ERBA,ERBA1,NR1A1,THRA1,THRA2,c-ERBA-1,Epigenetics & Nuclear Signaling,Transcription Factors,Nuclear Receptor Signaling,Nuclear hormone receptors,Cancer,Signal Transduction,Cell Biology & Developmental Biology,Growth factor,Endocrine & Metabolism,Neuroscience,THRA

Molecular Weight: 46 kDa/50 kDa/54 kDa

Gene ID: 7067

UniProt: P10827

Pathways: Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway, Sensory Perception of Sound, Cellular Response to Molecule of Bacterial Origin, Regulation of Lipid Metabolism by PPARalpha, Regulation of Muscle Cell Differentiation, Maintenance of Protein Location, Skeletal Muscle Fiber Development