TICAM1 antibody (AA 20-200)

Catalog No. ABIN6149148

This Rabbit Polyclonal antibody specifically detects TICAM1 in WB. It exhibits reactivity toward Human.

Quick Overview for TICAM1 antibody (AA 20-200) (ABIN6149148)

Target: TICAM1 (Toll-Like Receptor Adaptor Molecule 1 (TICAM1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TICAM1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-TICAM1 Antibody

Binding Specificity: AA 20-200

Sequence: QDKLLYLKHK LKTPRPGCQG QDLLHAMVLL KLGQETEARI SLEALKADAV ARLVARQWAG VDSTEDPEEP PDVSWAVARL YHLLAEEKLC PASLRDVAYQ EAVRTLSSRD DHRLGELQDE ARNRCGWDIA GDPGSIRTLQ SNLGCLPPSS ALPSGTRSLP RPIDGVSDWS QGCSLRSTGS P

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 20-200 of human TICAM1 (NP_891549.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for TICAM1

Target: TICAM1 (Toll-Like Receptor Adaptor Molecule 1 (TICAM1))

Alternative Name: TICAM1

Background: This gene encodes an adaptor protein containing a Toll/interleukin-1 receptor (TIR) homology domain, which is an intracellular signaling domain that mediates protein-protein interactions between the Toll-like receptors (TLRs) and signal-transduction components. This protein is involved in native immunity against invading pathogens. It specifically interacts with toll-like receptor 3, but not with other TLRs, and this association mediates dsRNA induction of interferon-beta through activation of nuclear factor kappa-B, during an antiviral immune response.,IIAE6,MyD88-3,PRVTIRB,TICAM-1,TRIF,TRIF/TICAM1,TICAM1,Immunology & Inflammation,Cytokines,Interferons,Toll-like Receptor Signaling Pathway,Cell Intrinsic Innate Immunity Signaling Pathway,TLR Signaling,TICAM1

Molecular Weight: 76 kDa

Gene ID: 148022

UniProt: Q8IUC6

Pathways: TLR Signaling, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Hepatitis C, Toll-Like Receptors Cascades