TIMP3 antibody (C-Term)

Catalog No. ABIN6149180

This Rabbit Polyclonal antibody specifically detects TIMP3 in WB. It exhibits reactivity toward Human.

Quick Overview for TIMP3 antibody (C-Term) (ABIN6149180)

Target: TIMP3 (TIMP Metallopeptidase Inhibitor 3 (TIMP3))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TIMP3 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-TIMP3 Antibody

Binding Specificity: C-Term

Sequence: YQYLLTGRVY DGKMYTGLCN FVERWDQLTL SQRKGLNYRY HLGCNCKIKS CYYLPCFVTS KNECLWTDML SNFGYPGYQS KHYACIRQKG GYCSWYRGWA PPDKSIINAT DP

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Immunogen: A synthetic peptide corresponding to a sequence within amino acids 100 to the C-terminus of human TIMP3 (NP_000353.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for TIMP3

Target: TIMP3 (TIMP Metallopeptidase Inhibitor 3 (TIMP3))

Alternative Name: TIMP3

Background: This gene belongs to the TIMP gene family. The proteins encoded by this gene family are inhibitors of the matrix metalloproteinases, a group of peptidases involved in degradation of the extracellular matrix (ECM). Expression of this gene is induced in response to mitogenic stimulation and this netrin domain-containing protein is localized to the ECM. Mutations in this gene have been associated with the autosomal dominant disorder Sorsby's fundus dystrophy.,TIMP3,HSMRK222,K222,K222TA2,SFD,Cancer,Invasion and Metastasis,Signal Transduction,Cell Biology & Developmental Biology,Apoptosis,Cytoskeleton,Extracellular Matrix,MMPs,Ubiquitin,Neuroscience,Cardiovascular,Angiogenesis,TIMP3

Molecular Weight: 24 kDa

Gene ID: 7078

UniProt: P35625