TRIM21 antibody (AA 80-330)

Catalog No. ABIN6149506

This Rabbit Polyclonal antibody specifically detects TRIM21 in WB, IHC, IP and IF. It exhibits reactivity toward Human.

Quick Overview for TRIM21 antibody (AA 80-330) (ABIN6149506)

Target: TRIM21 (Tripartite Motif Containing 21 (TRIM21))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TRIM21 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP), Immunofluorescence (IF)

Product Details anti-TRIM21 Antibody

Binding Specificity: AA 80-330

Sequence: SQEAREGTQG ERCAVHGERL HLFCEKDGKA LCWVCAQSRK HRDHAMVPLE EAAQEYQEKL QVALGELRRK QELAEKLEVE IAIKRADWKK TVETQKSRIH AEFVQQKNFL VEEEQRQLQE LEKDEREQLR ILGEKEAKLA QQSQALQELI SELDRRCHSS ALELLQEVII VLERSESWNL KDLDITSPEL RSVCHVPGLK KMLRTCAVHI TLDPDTANPW LILSEDRRQV RLGDTQQSIP GNEERFDSYP M

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 80-330 of human TRIM21 (NP_003132.2).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200,IP,1:20 - 1:50

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for TRIM21

Target: TRIM21 (Tripartite Motif Containing 21 (TRIM21))

Alternative Name: TRIM21

Background: This gene encodes a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The encoded protein is part of the RoSSA ribonucleoprotein, which includes a single polypeptide and one of four small RNA molecules. The RoSSA particle localizes to both the cytoplasm and the nucleus. RoSSA interacts with autoantigens in patients with Sjogren syndrome and systemic lupus erythematosus. Alternatively spliced transcript variants for this gene have been described but the full-length nature of only one has been determined.,TRIM21,RNF81,RO52,Ro/SSA,SSA,SSA1,Epigenetics & Nuclear Signaling,Immunology & Inflammation,TRIM21

Molecular Weight: 45 kDa/54 kDa

Gene ID: 6737

UniProt: P19474