UBTF antibody (AA 200-440)

Catalog No. ABIN6149866

This Rabbit Polyclonal antibody specifically detects UBTF in WB. It exhibits reactivity toward Human.

Quick Overview for UBTF antibody (AA 200-440) (ABIN6149866)

Target: UBTF (Upstream Binding Transcription Factor, RNA Polymerase I (UBTF))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This UBTF antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-UBTF Antibody

Binding Specificity: AA 200-440

Sequence: KTPQQLWYTH EKKVYLKVRP DATTKEVKDS LGKQWSQLSD KKRLKWIHKA LEQRKEYEEI MRDYIQKHPE LNISEEGITK STLTKAERQL KDKFDGRPTK PPPNSYSLYC AELMANMKDV PSTERMVLCS QQWKLLSQKE KDAYHKKCDQ KKKDYEVELL RFLESLPEEE QQRVLGEEKM LNINKKQATS PASKKPAQEG GKGGSEKPKR PVSAMFIFSE EKRRQLQEER PELSESELTR L

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 200-440 of human UBTF (NP_055048.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for UBTF

Target: UBTF (Upstream Binding Transcription Factor, RNA Polymerase I (UBTF))

Alternative Name: UBTF

Background: This gene encodes a member of the HMG-box DNA-binding protein family. The encoded protein plays a critical role in ribosomal RNA transcription as a key component of the pre-initiation complex, mediating the recruitment of RNA polymerase I to rDNA promoter regions. The encoded protein may also play important roles in chromatin remodeling and pre-rRNA processing, and its activity is regulated by both phosphorylation and acetylation. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. Pseudogenes of this gene are located on the short arm of chromosomes 3, 11 and X and the long arm of chromosome 11.,UBTF,NOR-90,UBF,UBF-1,UBF1,UBF2,Epigenetics & Nuclear Signaling,Transcription Factors,Signal Transduction,MAPK-Erk Signaling Pathway,UBTF

Molecular Weight: 84 kDa/89 kDa

Gene ID: 7343

UniProt: P17480