Uroplakin 1B antibody (AA 110-230)

Catalog No. ABIN6149946

The Rabbit Polyclonal anti-Uroplakin 1B antibody has been validated for WB. It is suitable to detect Uroplakin 1B in samples from Human.

Quick Overview for Uroplakin 1B antibody (AA 110-230) (ABIN6149946)

Target: Uroplakin 1B (UPK1B)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Uroplakin 1B antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-Uroplakin 1B Antibody

Binding Specificity: AA 110-230

Sequence: ATQQDFFTPN LFLKQMLERY QNNSPPNNDD QWKNNGVTKT WDRLMLQDNC CGVNGPSDWQ KYTSAFRTEN NDADYPWPRQ CCVMNNLKEP LNLEACKLGV PGFYHNQGCY ELISGPMNRH A

Cross-Reactivity: Human, Mouse

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 110-230 of human UPK1B (NP_008883.2).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Comment:

HIGH QUALITY

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for Uroplakin 1B

Target: Uroplakin 1B (UPK1B)

Alternative Name: UPK1B

Background: The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is found in the asymmetrical unit membrane (AUM) where it can form a complex with other transmembrane 4 superfamily proteins. It may play a role in normal bladder epithelial physiology, possibly in regulating membrane permeability of superficial umbrella cells or in stabilizing the apical membrane through AUM/cytoskeletal interactions. The use of alternate polyadenylation sites has been found for this gene.,UPK1B,TSPAN20,UPIB,UPK1,Signal Transduction,UPK1B

Molecular Weight: 29 kDa

Gene ID: 7348

UniProt: O75841