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Uroplakin 1B antibody (AA 109-229)

UPK1B Reactivity: Human ELISA, Coat, IHC (f) Host: Mouse Monoclonal UPK1B-3102 unconjugated
Catalog No. ABIN6938733
  • Target See all Uroplakin 1B (UPK1B) Antibodies
    Uroplakin 1B (UPK1B)
    Binding Specificity
    • 8
    • 7
    • 7
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 109-229
    Reactivity
    • 25
    • 3
    • 2
    Human
    Host
    • 20
    • 5
    Mouse
    Clonality
    • 20
    • 5
    Monoclonal
    Conjugate
    • 15
    • 2
    • 2
    • 2
    • 2
    • 2
    This Uroplakin 1B antibody is un-conjugated
    Application
    • 20
    • 18
    • 8
    • 7
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    ELISA, Coating (Coat), Immunohistochemistry (Formalin-fixed Sections) (IHC (f))
    Specificity
    The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is found in the asymmetrical unit membrane (AUM) where it can form a complex with other transmembrane 4 superfamily proteins. It may play a role in normal bladder epithelial physiology, possibly in regulating membrane permeability of superficial umbrella cells or in stabilizing the apical membrane through AUM/cytoskeletal interactions.UPK1B is expressed by terminally differentiated urothelial cells.
    Cross-Reactivity (Details)
    Human.
    Purification
    1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
    Immunogen
    Recombinant fragment (around aa 109-229) of human Uroplakin 1B (UPK1B) protein (exact sequence is proprietary)
    Clone
    UPK1B-3102
    Isotype
    IgG1 kappa
    Top Product
    Discover our top product UPK1B Primary Antibody
  • Application Notes

    Known_Application: ELISA (For coating, order Ab without BSA), Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT)(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes), Optimal dilution for a specific application should be determined.

    Positive_Control: Urinary Bladder.

    Restrictions
    For Research Use only
  • Concentration
    1.0 mg/mL
    Buffer
    Prepared in 10 mM PBS, WITHOUT BSA and Azide.
    Preservative
    Azide free
    Storage
    -20 °C,-80 °C
    Storage Comment
    Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
    Expiry Date
    24 months
  • Target
    Uroplakin 1B (UPK1B)
    Alternative Name
    UPK1B (UPK1B Products)
    Synonyms
    MGC81971 antibody, upk1b antibody, MGC81493 antibody, UPK1B antibody, TSPAN20 antibody, UPIB antibody, UPK1 antibody, AI413235 antibody, Tspan20 antibody, UPIb antibody, Upk1 antibody, uroplakin 1B antibody, uroplakin 1B S homeolog antibody, uroplakin 1A S homeolog antibody, UPK1B antibody, upk1b.S antibody, upk1a.S antibody, upk1b antibody, Upk1b antibody
    Background
    Tetraspanin-20, Tspan-20, TSPAN20, UP1b, UPIb, UPK1B, Uroplakin-1b,Uroplakin 1B (Urothelial Differentiation Marker)
    Cellular localisation: Cell Surface
    Molecular Weight
    30kDa
    Gene ID
    7348, 271580
    UniProt
    O75841
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