Vimentin antibody (AA 1-101)

Catalog No. ABIN6150108

The Rabbit Polyclonal anti-Vimentin antibody has been validated for WB, IHC and IF. It is suitable to detect Vimentin in samples from Human. There are 2+ publications available.

Quick Overview for Vimentin antibody (AA 1-101) (ABIN6150108)

Target: Vimentin (VIM)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Vimentin antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-Vimentin Antibody

Binding Specificity: AA 1-101

Sequence: MSTRSVSSSS YRRMFGGPGT ASRPSSSRSY VTTSTRTYSL GSALRPSTSR SLYASSPGGV YATRSSAVRL RSSVPGVRLL QDSVDFSLAD AINTEFKNTR T

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-101 of human Vimentin (NP_003371.2).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200

Comment:

HIGH QUALITY

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

References for anti-Vimentin antibody (ABIN6150108)

Wang, Wang, Tang, Zhang, Zheng, Wang, Zhang, Wang, Xie: "Direct inhibition of ACTN4 by ellagic acid limits breast cancer metastasis via regulation of β-catenin stabilization in cancer stem cells." in: Journal of experimental & clinical cancer research : CR, Vol. 36, Issue 1, pp. 172, (2018) (PubMed).

Wang, Zheng, Gu, Cai, Wang, Zhang, Chen, Situ, Lin, Wang: "Network-pharmacology-based validation of TAMS/CXCL-1 as key mediator of XIAOPI formula preventing breast cancer development and metastasis." in: Scientific reports, Vol. 7, Issue 1, pp. 14513, (2017) (PubMed).

Target Details for Vimentin

Target: Vimentin (VIM)

Alternative Name: VIM

Background: This gene encodes a member of the intermediate filament family. Intermediate filamentents, along with microtubules and actin microfilaments, make up the cytoskeleton. The protein encoded by this gene is responsible for maintaining cell shape, integrity of the cytoplasm, and stabilizing cytoskeletal interactions. It is also involved in the immune response, and controls the transport of low-density lipoprotein (LDL)-derived cholesterol from a lysosome to the site of esterification. It functions as an organizer of a number of critical proteins involved in attachment, migration, and cell signaling. Mutations in this gene causes a dominant, pulverulent cataract.,CTRCT30,HEL113,Vimentin,VIM,vimentin,Cancer,Tumor biomarkers,Signal Transduction,Cell Biology & Developmental Biology,Cytoskeleton,Intermediate Filaments,Neuroscience,Cell Type Marker,Stem Cells,Neural Stem Cells,Neural Stem Cell marker,VIM

Molecular Weight: 53 kDa

Gene ID: 7431

UniProt: P08670

Pathways: Caspase Cascade in Apoptosis