Vimentin antibody

Catalog No. ABIN1881993

Product Details anti-Vimentin Antibody

Target: Vimentin (VIM)

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Vimentin antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This Vimentin antibody is generated from rabbits immunized with human Vimentin recombinant protein.

Clone: RB41034

Isotype: Ig Fraction

Application Details

Application Notes: IF: 1:50. IF: 1:50. IF: 1:50. WB: 1:4000. WB: 1:2000. IHC-P-Leica: 1:500. IHC-P-Leica: 1:500

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Expiry Date: 6 months

References for anti-Vimentin antibody (ABIN1881993)

Fuechsle, Mahapatra, Zwanenburg, Friesen, Eriksson, Simmons: "Spectroscopy of few-electron single-crystal silicon quantum dots." in: Nature nanotechnology, Vol. 5, Issue 7, pp. 502-5, (2010) (PubMed).

Li, Zhang, Sun, Wang, Ban, Sun, Liu, Zhao: "A novel function for vimentin: the potential biomarker for predicting melanoma hematogenous metastasis." in: Journal of experimental & clinical cancer research : CR, Vol. 29, pp. 109, (2010) (PubMed).

Korita, Wakai, Ajioka, Inoue, Takamura, Shirai, Hatakeyama: "Aberrant expression of vimentin correlates with dedifferentiation and poor prognosis in patients with intrahepatic cholangiocarcinoma." in: Anticancer research, Vol. 30, Issue 6, pp. 2279-85, (2010) (PubMed).

Target Details for Vimentin

Target: Vimentin (VIM)

Alternative Name: Vimentin (VIM Products)

Synonyms: CTRCT30 antibody, cb28 antibody, vime antibody, vim antibody, vim1 antibody, vim2 antibody, VIM antibody, Vimentin antibody, vim4 antibody, vimentin antibody, vimentin L homeolog antibody, vimentin S homeolog antibody, VIM antibody, Vim antibody, vim antibody, vim.L antibody, vim.S antibody

Background: This gene encodes a member of the intermediate filament family. Intermediate filamentents, along with microtubules and actin microfilaments, make up the cytoskeleton. The protein encoded by this gene is responsible for maintaining cell shape, integrity of the cytoplasm, and stabilizing cytoskeletal interactions. It is also involved in the immune response, and controls the transport of low-density lipoprotein (LDL)-derived cholesterol from a lysosome to the site of esterification. It functions as an organizer of a number of critical proteins involved in attachment, migration, and cell signaling. Mutations in this gene causes a dominant, pulverulent cataract.

Molecular Weight: 53652

NCBI Accession: NP_003371

UniProt: P08670

Pathways: Caspase Cascade in Apoptosis