VPS33B antibody (AA 348-617)

Catalog No. ABIN6150128

The Rabbit Polyclonal anti-VPS33B antibody has been validated for WB and IF. It is suitable to detect VPS33B in samples from Human.

Quick Overview for VPS33B antibody (AA 348-617) (ABIN6150128)

Target: VPS33B (Vacuolar Protein Sorting-Associated Protein 33B (VPS33B))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This VPS33B antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF)

Product Details anti-VPS33B Antibody

Binding Specificity: AA 348-617

Sequence: CESIMKKKTK QDFQELIKTE HALLEGFNIR ESTSYIEEHI DRQVSPIESL RLMCLLSITE NGLIPKDYRS LKTQYLQSYG PEHLLTFSNL RRAGLLTEQA PGDTLTAVES KVSKLVTDKA AGKITDAFSS LAKRSNFRAI SKKLNLIPRV DGEYDLKVPR DMAYVFGGAY VPLSCRIIEQ VLERRSWQGL DEVVRLLNCS DFAFTDMTKE DKASSESLRL ILVVFLGGCT FSEISALRFL GREKGYRFIF LTTAVTNSAR LMEAMSEVKA

Cross-Reactivity: Human, Mouse

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 348-617 of human VPS33B (NP_061138.3).

Isotype: IgG

Application Details

Application Notes: WB,1:1000 - 1:2000,IF,1:50 - 1:200

Comment:

HIGH QUALITY

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for VPS33B

Target: VPS33B (Vacuolar Protein Sorting-Associated Protein 33B (VPS33B))

Alternative Name: VPS33B

Background: Vesicle mediated protein sorting plays an important role in segregation of intracellular molecules into distinct organelles. Genetic studies in yeast have identified more than 40 vacuolar protein sorting (VPS) genes involved in vesicle transport to vacuoles. This gene is a member of the Sec-1 domain family, and encodes the human ortholog of rat Vps33b which is homologous to the yeast class C Vps33 protein. The mammalian class C vacuolar protein sorting proteins are predominantly associated with late endosomes/lysosomes, and like their yeast counterparts, may mediate vesicle trafficking steps in the endosome/lysosome pathway. Mutations in this gene are associated with arthrogryposis-renal dysfunction-cholestasis syndrome. Alternative splicing results in multiple transcript variants.,VPS33B,Signal Transduction,VPS33B

Molecular Weight: 60 kDa/70 kDa

Gene ID: 26276

UniProt: Q9H267