VPS33B antibody (AA 361-460)

Catalog No. ABIN6945326

The Rabbit Polyclonal anti-VPS33B antibody (ABIN6945326) specifically detects VPS33B in IF (cc), IF (p), IHC (p) and IHC (fro). The antibody is reactive with Human samples.

Quick Overview for VPS33B antibody (AA 361-460) (ABIN6945326)

Target: VPS33B (Vacuolar Protein Sorting-Associated Protein 33B (VPS33B))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This VPS33B antibody is un-conjugated

Application: Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-VPS33B Antibody

Binding Specificity: AA 361-460

Purpose: VPS33B Polyclonal Antibody

Cross-Reactivity: Mouse

Predicted Reactivity: Human,Rat,Dog,Cow,Sheep,Horse,Chicken,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human VPS33B

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for VPS33B

Target: VPS33B (Vacuolar Protein Sorting-Associated Protein 33B (VPS33B))

Alternative Name: VPS33B

Background:

Synonyms: FLJ14848, hVPS 33B, hVPS33B, Vacuolar protein sorting 33 homolog B (yeast), Vacuolar protein sorting 33 homolog B, Vacuolar protein sorting 33B (yeast), Vacuolar protein sorting 33B, Vacuolar protein sorting associated protein 33B, VPS 33B.

Background: Vesicle mediated protein sorting plays an important role in segregation of intracellular molecules into distinct organelles. Genetic studies in yeast have identified more than 40 vacuolar protein sorting (VPS) genes involved in vesicle transport to vacuoles. This gene is a member of the Sec-1 domain family, and encodes the human ortholog of rat Vps33b which is homologous to the yeast class C Vps33 protein. The mammalian class C vacuolar protein sorting proteins are predominantly associated with late endosomes/lysosomes, and like their yeast counterparts, may mediate vesicle trafficking steps in the endosome/lysosome pathway. Mutations in this gene are associated with arthrogryposis-renal dysfunction-cholestasis syndrome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2014]

Gene ID: 608552

UniProt: Q9H267