WDR35 antibody (AA 871-1170)

Catalog No. ABIN6150192

The Rabbit Polyclonal anti-WDR35 antibody has been validated for WB and IF. It is suitable to detect WDR35 in samples from Human.

Quick Overview for WDR35 antibody (AA 871-1170) (ABIN6150192)

Target: WDR35 (WD Repeat Domain 35 (WDR35))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This WDR35 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF)

Product Details anti-WDR35 Antibody

Binding Specificity: AA 871-1170

Sequence: CSQPKAAVDT CVHLNQWNKA VELAKNHSMK EIGSLLARYA SHLLEKNKTL DAIELYRKAN YFFDAAKLMF KIADEEAKKG SKPLRVKKLY VLSALLIEQY HEQMKNAQRG KVKGKSSEAT SALAGLLEEE VLSTTDRFTD NAWRGAEAYH FFILAQRQLY EGCVDTALKT ALHLKDYEDI IPPVEIYSLL ALCACASRAF GTCSKAFIKL KSLETLSSEQ KQQYEDLALE IFTKHTSKDN RKPELDSLME GGEGKLPTCV ATGSPITEYQ FWMCSVCKHG VLAQEISHYS FCPLCHSPVG

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 871-1170 of human WDR35 (NP_065830.2).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:1000,IF,1:50 - 1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for WDR35

Target: WDR35 (WD Repeat Domain 35 (WDR35))

Alternative Name: WDR35

Background: This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. Two patients with Sensenbrenner syndrome / cranioectodermal dysplasia (CED) were identified with mutations in this gene, consistent with a possible ciliary function.,WDR35,CED2,IFT121,IFTA1,SRTD7,Cell Biology & Developmental Biology,WDR35

Molecular Weight: 132 kDa/133 kDa

Gene ID: 57539

UniProt: Q9P2L0

Pathways: Hedgehog Signaling