WNT5A antibody (AA 250-350)

Catalog No. ABIN6150248

Product Details anti-WNT5A Antibody

Target: WNT5A (Wingless-Type MMTV Integration Site Family, Member 5A (WNT5A))

Binding Specificity: AA 250-350

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This WNT5A antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF)

Sequence: KTCWLQLADF RKVGDALKEK YDSAAAMRLN SRGKLVQVNS RFNSPTTQDL VYIDPSPDYC VRNESTGSLG TQGRLCNKTS EGMDGCELMC CGRGYDQFKT V

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Immunogen: A synthetic peptide corresponding to a sequence within amino acids 250-350 of human WNT5A (NP_003383.2).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IF,1:50 - 1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for WNT5A

Target: WNT5A (Wingless-Type MMTV Integration Site Family, Member 5A (WNT5A))

Alternative Name: WNT5A (WNT5A Products)

Background: The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene encodes a member of the WNT family that signals through both the canonical and non-canonical WNT pathways. This protein is a ligand for the seven transmembrane receptor frizzled-5 and the tyrosine kinase orphan receptor 2. This protein plays an essential role in regulating developmental pathways during embryogenesis. This protein may also play a role in oncogenesis. Mutations in this gene are the cause of autosomal dominant Robinow syndrome. Alternate splicing results in multiple transcript variants.,hWNT5A,Wnt5a,WNT5A,Epigenetics & Nuclear Signaling,Translation Control,Regulation of eIF4 and p70 S6 Kinase,Cancer,Tumor suppressors,Signal Transduction,G protein signaling,mTOR Signaling Pathway,Cell Biology & Developmental Biology,Microtubules,Wnt/β-Catenin Signaling Pathway,ESC Pluripotency and Differentiation,Neuroscience,Stem Cells,WNT5A

Molecular Weight: 40 kDa/42 kDa

Gene ID: 7474

UniProt: P41221

Pathways: WNT Signaling, Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Regulation of Cell Size, Tube Formation