ZCWPW1 antibody (AA 389-648)

Catalog No. ABIN6150412

This Rabbit Polyclonal antibody specifically detects ZCWPW1 in WB. It exhibits reactivity toward Human.

Quick Overview for ZCWPW1 antibody (AA 389-648) (ABIN6150412)

Target: ZCWPW1 (Zinc Finger, CW Type with PWWP Domain 1 (ZCWPW1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ZCWPW1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-ZCWPW1 Antibody

Binding Specificity: AA 389-648

Sequence: VMKKRRNDCS QKLGVALMMA QEAEQISIQE RVNLFGFWSR FNGSNSNGER KDLQLSGLNS PGSCLEKKEK EEELEKEEGE KTDPILPIRK RVKIQTQKTK PRGLGGDAGT ADGRGRTLQR KIMKRSLGRK STAPPAPRMG RKEGQGNSDS DQPGPKKKFK APQSKALAAS FSEGKEVRTV PKNLGLSACK GACPSSAKEE PRHREPLTQE AGSVPLEDEA SSDLDLEQLM EDVGRELGQS GELQHSNSDG EDFPVALFGK

Cross-Reactivity: Human, Mouse

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 389-648 of human ZCWPW1 (NP_060454.3).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Comment:

HIGH QUALITY

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for ZCWPW1

Target: ZCWPW1 (Zinc Finger, CW Type with PWWP Domain 1 (ZCWPW1))

Alternative Name: ZCWPW1

Background: Dual histone methylation reader specific for PRDM9-catalyzed histone marks (H3K4me3 and H3K36me3. Facilitates the repair of PRDM9-induced meiotic double-strand breaks (DSBs (By similarity. Essential for male fertility and spermatogenesis (By similarity. Required for meiosis prophase I progression in male but not in female germ cells (By similarity.,ZCWPW1,ZCW1,Epigenetics & Nuclear Signaling,Cell Biology & Developmental Biology,ZCWPW1

Molecular Weight: 45 kDa/52 kDa/53 kDa/59 kDa/72 kDa

Gene ID: 55063

UniProt: Q9H0M4