MMP3 antibody

Catalog No. ABIN615180

The Rabbit Polyclonal anti-MMP3 antibody (ABIN615180) specifically detects MMP3 in WB and IHC (p). The antibody is reactive with Human, Rat, Mouse, Rabbit and Horse samples.

Quick Overview for MMP3 antibody (ABIN615180)

Target: MMP3 (Matrix Metallopeptidase 3 (Stromelysin 1, Progelatinase) (MMP3))

Reactivity: Human, Rat, Mouse, Rabbit, Horse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MMP3 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-MMP3 Antibody

Specificity: The antibody recognizes the MMP-3. The antibody detects the 55 kDa full length and the 21 kDa cleavage fragment of MMP-3.

Purification: Affinity Chromatography

Immunogen: Synthetic peptide surrounding amino acid 465 of Rat MMP-3

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 0.5 mg/mL

Buffer: PBS containing 30 % Glycerol, 0.5 % BSA and 0.01 % Thimerosal

Preservative: Thimerosal (Merthiolate)

Precaution of Use: This product contains thimerosal (merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for MMP3

Target: MMP3 (Matrix Metallopeptidase 3 (Stromelysin 1, Progelatinase) (MMP3))

Alternative Name: MMP-3

Background: MMP3 is a Metallopeptidase M10A type protease. Human fibroblast stromelysin/MMP3 is a proteoglycanase with a wide range of substrate specificities. It is a secreted metalloprotease produced predominantly by connective tissue cells. MMP3 is capable of degrading proteoglycan, fibronectin, laminin, and type IV collagen. Expression has been documented in breast carcinoma, wound healing and chronic inflammatory diseases.Synonyms: MMP3, Matrix metalloproteinase-3, SL-1, STMY1, Stromelysin-1, Transin-1

Gene ID: 4314

NCBI Accession: NP_002413

UniProt: P08254