IKZF1 antibody (Internal Region)

Catalog No. ABIN615922

This Goat Polyclonal antibody specifically detects IKZF1 in WB, IHC (p) and EIA. It exhibits reactivity toward Human, Dog and Cow.

Quick Overview for IKZF1 antibody (Internal Region) (ABIN615922)

Target: IKZF1 (IKAROS Family Zinc Finger 1 (Ikaros) (IKZF1))

Reactivity: Human, Dog, Cow

Host: Goat

Clonality: Polyclonal

Conjugate: This IKZF1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Product Details anti-IKZF1 Antibody

Binding Specificity: Internal Region

Sequence: C-DTPYDSSASY EKEN

Specificity: This antibody recognizes IKAROS.

Cross-Reactivity (Details): Species reactivity (expected):Canine (Dog) and Bovine.
Species reactivity (tested):Human.

Purification: Ammonium Sulphate Precipitation followed by antigen Affinity Chromatography using the immunizing peptide

Immunogen: Peptide with sequence from the internal region of the protein sequence according to NP_006051.1. Genename: IKZF1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 0.5 mg/mL

Buffer: Tris buffered saline, pH ~7.3 containing 0.02 % Sodium Azide as preservative and 0.5 % BSA as stabilizer

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for IKZF1

Target: IKZF1 (IKAROS Family Zinc Finger 1 (Ikaros) (IKZF1))

Alternative Name: IKZF1 / IKAROS

Background: DNA-binding protein IKAROS functions in the specification and the maturation of the T lymphocyte. It also interacts with a critical control element in the terminal deoxynucleotidyl transferase promoter as well as with the promoters for other genes expressed during early stages of B-cell and T-cell development.Synonyms: DNA-binding protein Ikaros, IK1, Ikaros family zinc finger protein 1, LYF-1, LYF1, Lymphoid transcription factor LyF-1, ZNFN1A1

Gene ID: 10320

NCBI Accession: NP_006051

UniProt: Q13422

Pathways: Production of Molecular Mediator of Immune Response