Prolactin Receptor antibody (CF®488A)

Catalog No. ABIN6167155

The Mouse Monoclonal anti-Prolactin Receptor antibody has been validated for FACS, IF and IHC (f). It is suitable to detect Prolactin Receptor in samples from Human.

Quick Overview for Prolactin Receptor antibody (CF®488A) (ABIN6167155)

Target: Prolactin Receptor (PRLR)

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Prolactin Receptor antibody is conjugated to CF®488A

Application: Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (Formalin-fixed Sections) (IHC (f))

Clone: B6-2 PRLR742

Product Details anti-Prolactin Receptor Antibody (CF®488A)

Purpose: Mouse Monoclonal anti-Prolactin Receptor (B6.2 + PRLR742), CF488A Conjugate

Characteristics: This antibody recognizes a protein of 70 kDa, identified as prolactin receptor. Prolactin is a pituitary hormone involved in the stimulation of milk production, salt and water regulation, growth, development and reproduction. The initial step in its action is the binding to a specific membrane receptor (prolactin receptor), which belongs to the superfamily of class 1 cytokine receptors. The function of the prolactin receptor is mediated, at least in part, by two families of signaling molecules: Janus kinases and signal transducers and activators of transcription. Primary antibodies are available purified, or with a selection of fluorescent CF ® dyes and other labels. CF ® dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF ®405S and CF ®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Immunogen: Semi-purified human prolactin receptor (B6.2), Recombinant human prolactin receptor (PRLR742)

Isotype: IgG

Application Details

Application Notes: Immunohistology formalin-fixed 0.5-1 μg/mL

• Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer,  pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes
• Immunofluorescence 0.5-1 μg/mL
• Flow Cytometry 0.5-1 μg/million cells/0.1 mL
• Optimal dilution for a specific application should be determined by user

Comment:

Testicular Carcinoma

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 100 μg/mL

Buffer: PBS/0.1 % BSA/0.05 % azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Protect from light

Target Details for Prolactin Receptor

Target: Prolactin Receptor (PRLR)

Alternative Name: Prolactin Receptor

Background: CPRLP|hPRL receptor|hPRLrI|Lactogen receptor|OPR|Pr-1|Pr-3|PRL-R|Prolactin receptor delta 7/11|RATPRLR|Secreted prolactin binding protein|Truncated testis-specific box 1-C prolactin receptor

Molecular Weight: 70 kDa

Gene ID: 5618, 368587

UniProt: P16471

Pathways: JAK-STAT Signaling, Response to Growth Hormone Stimulus