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CD37 antibody (Tetraspanin 26) Primary Antibody

TSPAN26 Reactivity: Human FACS, IF Host: Mouse Monoclonal IPO-24 unconjugated
Catalog No. ABIN6172623
$306.46
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  • Target See all CD37 (TSPAN26) Antibodies
    CD37 (TSPAN26)
    Reactivity
    • 74
    • 8
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Human
    Host
    • 41
    • 35
    Mouse
    Clonality
    • 41
    • 35
    Monoclonal
    Conjugate
    • 32
    • 7
    • 7
    • 5
    • 4
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CD37 antibody is un-conjugated
    Application
    • 49
    • 34
    • 28
    • 27
    • 14
    • 9
    • 6
    • 5
    • 5
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    Flow Cytometry (FACS), Immunofluorescence (IF)
    Purpose
    Mouse Monoclonal anti-CD37 (IPO-24), Purified, with BSA
    Characteristics
    This antibody recognizes a protein of 33-55 kDa, identified as CD37 (Workshop V, Code CD37.7). CD37 is strongly expressed on normal and neoplastic mature (sIg ) B-lymphocytes. In B-cell ontogeny, CD37 appears after the pre-B-cell stage, is maintained during peripheral B-cell development and is lost upon terminal differentiation into plasma cells.1 CD37 is also present, at low densities, on resting and activated T cells, neutrophils, monocytes, and some myelomonocytic leukemia cells. It is absent from platelets, erythrocytes. CD37 is a member of a family of tetraspan transmembrane proteins, including CD9, CD53, CD63, CD81, and CD82. It associates other tetraspan transmembrane proteins and MHC class II molecules to form a large complex at the surface of B cells and play a role in signal transduction. CD37 is a valuable and stable marker for peripheral mature B-cells and corresponding malignancies like B-cell chronic lymphocytic leukemia (B-CLL), hairy cell leukemia (HCL), and all types of B-cell non-Hodgkin'' lymphoma (B-NHL). Primary antibodies are available purified, or with a selection of fluorescent CF® dyes and other labels. CF® dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
    Purification
    Purified
    Immunogen
    Spleen cells of a patient with hairy cell leukemia
    Clone
    IPO-24
    Isotype
    IgG2b kappa
  • Application Notes
    Immunofluorescence 0.5-1 μg/mL
    • Flow Cytometry 0.5-1 μg/million cells/0.1 mL
    • Optimal dilution for a specific application should be determined by user
    Comment

    Daudi, Raji, Namalva, Ramos cells and human lymphocytes. Human tonsil and lymph node.

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    200 μg/mL
    Buffer
    PBS/0.05 % BSA/0.05 % azide
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Target
    CD37 (TSPAN26)
    Alternative Name
    CD37 (TSPAN26 Products)
    Synonyms
    Tspan26, GP52-40, TSPAN26, CD37 antigen, CD37 molecule, Cd37, CD37
    Background
    Cell differentiation antigen 37, GP52 40, Tetraspanin-26, Tspan-26, TSPAN26
    Molecular Weight
    33-55 kDa
    Gene ID
    951, 166556
    UniProt
    P11049
    Pathways
    Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response
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