Tyrosine Hydroxylase antibody

Catalog No. ABIN617906

The Mouse Monoclonal anti-Tyrosine Hydroxylase antibody has been validated for WB, IHC, IF, ICC and IEM. It is suitable to detect Tyrosine Hydroxylase in samples from Human, Rat, Mouse, Dog, Rabbit, Chicken, Drosophila melanogaster, Pig, Zebrafish (Danio rerio), Xenopus laevis, Guinea Pig, Cat, Ferret, Salmon, Salamander, Saccharomyces cerevisiae, Rodents, Quail, Polypterus senegalus, Pigeon, Phoronida, Parrot (Melopsittacus), Parrot, Opossum, Onchocerca, Newt, Zebra Finch, Mollusca, Sea Pansy, Sea Slug, Serinus canaria, Shark, Sheep, Shrew, Snail, Snake, Sparrow, Squirrel Monkey, Starling, Trout, Turkey, Turtle, Water Buffalo, Emu, Alpaca, Amphibian, Aplysia californica, Avian, Bee, Blow Fly, Clams (Mytilus), Cockroach, Cod, Coral, Crab, Crayfish, Cynomolgus, Echidna, Macrobrachium rosenbergii (Giant fresh water prawn), Fish, Fox, Frog, Gecko, Gerbil, Goldfish, Guppy, Hamster, Iguana iguana, Lamprey, Leech, Lizard, Lobster and Locust (Schistocerca). There are 1,443+ publications available.

Quick Overview for Tyrosine Hydroxylase antibody (ABIN617906)

Target: Tyrosine Hydroxylase (TH)

Reactivity: Human, Rat, Mouse, Dog, Rabbit, Chicken, Drosophila melanogaster, Pig, Zebrafish (Danio rerio), Xenopus laevis, Guinea Pig, Cat, Ferret, Salmon, Salamander, Saccharomyces cerevisiae, Rodents, Quail, Polypterus senegalus, Pigeon, Phoronida, Parrot (Melopsittacus), Parrot, Opossum, Onchocerca, Newt, Zebra Finch, Mollusca, Sea Pansy, Sea Slug, Serinus canaria, Shark, Sheep, Shrew, Snail, Snake, Sparrow, Squirrel Monkey, Starling, Trout, Turkey, Turtle, Water Buffalo, Emu, Alpaca, Amphibian, Aplysia californica, Avian, Bee, Blow Fly, Clams (Mytilus), Cockroach, Cod, Coral, Crab, Crayfish, Cynomolgus, Echidna, Macrobrachium rosenbergii (Giant fresh water prawn), Fish, Fox, Frog, Gecko, Gerbil, Goldfish, Guppy, Hamster, Iguana iguana, Lamprey, Leech, Lizard, Lobster, Locust (Schistocerca)

Host: Mouse

Clonality: Monoclonal

Conjugate: This Tyrosine Hydroxylase antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC), Immunoelectron Microscopy (IEM)

Clone: LNC1

Product Details anti-Tyrosine Hydroxylase Antibody

Characteristics: The Tyrosine Hydroxylase antiserum was quality control tested using standard immunohistochemical methods. The antiserum demonstrates strongly positive labeling of rat catecholamine neuron systems using indirect immunofluorescent and biotin/avidin-HRP techniques. Recommended primary dilutions for these methods are provided below. This antibody does not cross react with dihydropterdine reductase, dopamine-B-hydroxylase, phenylethanolamine-N-methyltransferase, phenylalanine hydroxylase or tryptophan hydroxylase using Western blot methods.

Purification: Lyophilized ascites

Immunogen: TH

Isotype: IgG1

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Contains ≤ 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C/-20 °C

Storage Comment: After reconstitution, use immediately or refrigerate at 2 - 8 °C up to 2 days. For long-term storage aliquot antibody and freeze at -15 °C or lower. Avoid repeated freeze/thaw cycles.

References for anti-Tyrosine Hydroxylase antibody (ABIN617906)

Richard, Kozlowski, Guillorit, Garnier, McKnight, Danchin, Manière: "Queuine, a bacterial-derived hypermodified nucleobase, shows protection in in vitro models of neurodegeneration." in: PloS one, Vol. 16, Issue 8, pp. e0253216, (2021) (PubMed).

Soman, Bazała, Keatinge, Bandmann, Kuznicki: "Restriction of mitochondrial calcium overload by mcu inactivation renders a neuroprotective effect in zebrafish models of Parkinson's disease." in: Biology open, Vol. 8, Issue 10, (2019) (PubMed).

Yamaguchi, Ehara, Nakadate, Ueda: "Tyrosine hydroxylase afferents to the interstitial nucleus of the posterior limb of the anterior commissure are neurochemically distinct from those projecting to neighboring nuclei." in: Journal of chemical neuroanatomy, Vol. 90, pp. 98-107, (2017) (PubMed).

Morona, Ferran, Puelles, González: "Gene expression analysis of developing cell groups in the pretectal region of Xenopus laevis." in: The Journal of comparative neurology, Vol. 525, pp. 715-752, (2017) (PubMed).

Kordower, Vinuela, Chu, Isacson, Redmond: "Parkinsonian monkeys with prior levodopa-induced dyskinesias followed by fetal dopamine precursor grafts do not display graft-induced dyskinesias." in: The Journal of comparative neurology, Vol. 525, pp. 498-512, (2017) (PubMed).

Briski, Alenazi, Shakya, Sylvester: "Hindbrain A2 noradrenergic neuron adenosine 5'-monophosphate-activated protein kinase activation, upstream kinase/phosphorylase protein expression, and receptivity to hormone and fuel reporters of short-term food deprivation are regulated by estradiol." in: Journal of neuroscience research, Vol. 95, pp. 1427-1437, (2017) (PubMed).

Powers, Pacak, Tischler: "Pathology of Human Pheochromocytoma and Paraganglioma Xenografts in NSG Mice." in: Endocrine pathology, Vol. 28, pp. 2-6, (2017) (PubMed).

Medrano, Santamarta, Pablos, Aira, Buesa, Azkue, Mendiguren, Pineda: "Characterization of functional μ opioid receptor turnover in rat locus coeruleus: an electrophysiological and immunocytochemical study." in: British journal of pharmacology, Vol. 174, pp. 2758-2772, (2017) (PubMed).

Gagnon, Gregoire, Di Paolo, Parent: "Serotonin hyperinnervation of the striatum with high synaptic incidence in parkinsonian monkeys." in: Brain structure & function, Vol. 221, Issue 7, pp. 3675-91, (2017) (PubMed).

Panneton, Gan, Ariel: "Injections of Algesic Solutions into Muscle Activate the Lateral Reticular Formation: A Nociceptive Relay of the Spinoreticulothalamic Tract." in: PLoS ONE, Vol. 10, Issue 7, pp. e0130939, (2016) (PubMed).

Schovanek, Bullova, Tayem, Giubellino, Wesley, Lendvai, Nölting, Kopacek, Frysak, Pommier, Kummar, Pacak: "Inhibitory Effect of the Noncamptothecin Topoisomerase I Inhibitor LMP-400 on Female Mice Models and Human Pheochromocytoma Cells." in: Endocrinology, Vol. 156, Issue 11, pp. 4094-104, (2016) (PubMed).

Mor, Kang, Wyllie, Thirunavukarasu, Houlton, Austin, Keay: "Recruitment of dorsal midbrain catecholaminergic pathways in the recovery from nerve injury evoked disabilities." in: Molecular pain, Vol. 11, pp. 50, (2016) (PubMed).

Aguiar, Duzzioni, Remor, Tristão, Matheus, Raisman-Vozari, Latini, Prediger: "Moderate-Intensity Physical Exercise Protects Against Experimental 6-Hydroxydopamine-Induced Hemiparkinsonism Through Nrf2-Antioxidant Response Element Pathway." in: Neurochemical research, Vol. 41, Issue 1-2, pp. 64-72, (2016) (PubMed).

Aguiar, Lopes, Tristão, Rial, de Oliveira, da Cunha, Raisman-Vozari, Prediger: "Exercise Improves Cognitive Impairment and Dopamine Metabolism in MPTP-Treated Mice." in: Neurotoxicity research, Vol. 29, Issue 1, pp. 118-25, (2016) (PubMed).

Li, Fitzgerald, Del Mar, Cuthbertson-Coates, LeDoux, Gong, Ryan, Reiner et al.: "The identification and neurochemical characterization of central neurons that target parasympathetic preganglionic neurons involved in the regulation of choroidal blood flow in the rat eye using ..." in: Frontiers in neuroanatomy, Vol. 9, pp. 65, (2015) (PubMed).

Gompf, Budygin, Fuller, Bass: "Targeted genetic manipulations of neuronal subtypes using promoter-specific combinatorial AAVs in wild-type animals." in: Frontiers in behavioral neuroscience, Vol. 9, pp. 152, (2015) (PubMed).

Eid, Parent: "Morphological evidence for dopamine interactions with pallidal neurons in primates." in: Frontiers in neuroanatomy, Vol. 9, pp. 111, (2015) (PubMed).

Hashemian, ORourke, Phillips, Strömberg, Af Bjerkén: "Embryonic and mature astrocytes exert different effects on neuronal growth in rat ventral mesencephalic slice cultures." in: SpringerPlus, Vol. 4, pp. 558, (2015) (PubMed).

Ribeiro, Laguna Goya, Ravindran, Vuono, Parish, Foldi, Piroth, Yang, Parmar, Nikkhah, Hjerling-Leffler, Lindvall, Barker, Arenas: "Efficient expansion and dopaminergic differentiation of human fetal ventral midbrain neural stem cells by midbrain morphogens." in: Neurobiology of disease, Vol. 49, pp. 118-27, (2014) (PubMed).

van Kerkhof, Trezza, Mulder, Gao, Voorn, Vanderschuren: "Cellular activation in limbic brain systems during social play behaviour in rats." in: Brain structure & function, Vol. 219, Issue 4, pp. 1181-211, (2014) (PubMed).

Target Details for Tyrosine Hydroxylase

Target: Tyrosine Hydroxylase (TH)

Alternative Name: Tyrosine Hydroxylase

Background: Other Names:
Tyrosine 3-monooxygenase (TH),TYH,Tyrosine 3-hydroxylase

Gene ID: 25085

Pathways: Dopaminergic Neurogenesis, Response to Water Deprivation, Sensory Perception of Sound, Carbohydrate Homeostasis, Feeding Behaviour