UGT1A9 antibody (CF®594)

Catalog No. ABIN6180744

This Mouse Monoclonal antibody specifically detects UGT1A9 in IF and FACS. It exhibits reactivity toward Human.

Quick Overview for UGT1A9 antibody (CF®594) (ABIN6180744)

Target: UGT1A9 (UDP Glucuronosyltransferase 1 Family, Polypeptide A9 (UGT1A9))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This UGT1A9 antibody is conjugated to CF®594

Application: Immunofluorescence (IF), Flow Cytometry (FACS)

Clone: UGT1A9-1229

Product Details anti-UGT1A9 Antibody (CF®594)

Purpose: Mouse Monoclonal anti-UGT1A9 (UDP glucuronosyltransferase-1 family, polypeptide A9) (UGT1A9/1229), CF594 Conjugate

Characteristics: This antibody recognizes a protein of about 60 kDa, which is identified as human UGT1A9. It does not cross-react with the other UGT1A isoforms including UGT1A7, UGT1A8, and UGT1A10 and shows a high degree of specificity. UGT1A9 is a UDP-glucuronosyltransferase, an enzyme of the glucuronidation pathway that transforms small lipophilic molecules, such as steroids, bilirubin, hormones, and drugs, into water-soluble, excretable metabolites. This MAb binds to human hepatocytes and the majority of human hepatocellular carcinomas (HCC s). In frozen sections, it stains hepatic cells and may be used as a marker of the liver. This MAb also binds to cell preparations of hepatocellular carcinoma biopsies or cell lines. Primary antibodies are available purified, or with a selection of fluorescent CF® dyes and other labels. CF® dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Immunogen: A synthetic peptide specific to human UGT1A9 protein

Isotype: IgG2b kappa

Application Details

Application Notes: Immunofluorescence 0.5-1 μg/mL

• Flow Cytometry 0.5-1 μg/million cells/0.1 mL
• Optimal dilution for a specific application should be determined by user

Comment:

HepG2 cells. Liver or Hepatocellular Carcinoma (HCC)

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 100 μg/mL

Buffer: PBS/0.1 % BSA/0.05 % azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Protect from light

Target Details for UGT1A9

Target: UGT1A9 (UDP Glucuronosyltransferase 1 Family, Polypeptide A9 (UGT1A9))

Alternative Name: UGT1A9 (UDP glucuronosyltransferase-1 family, polypeptide A9)

Background: GNT1, HLUGP4, lugP4, UDP-glucuronosyltransferase 1-I, UDP-glucuronosyltransferase 1A9 (UGT1A9), UDPGT 1-9, UDPGT, UGT-1I, UGT1*9, UGT1-09, UGT1.9, Ugt1a9, UGT1I

Molecular Weight: 60 kDa

Gene ID: 54600, 554822

UniProt: O60656

Pathways: Steroid Hormone Biosynthesis, Regulation of Lipid Metabolism by PPARalpha