HIV-1 p24 antibody (CF®640R)

Catalog No. ABIN6186500

This anti-HIV-1 p24 antibody is a Mouse Monoclonal antibody detecting HIV-1 p24 in ELISA, IF, ICC and Coat. Suitable for Human Immunodeficiency Virus (HIV).

Quick Overview for HIV-1 p24 antibody (CF®640R) (ABIN6186500)

Target: HIV-1 p24 (Human Immunodeficiency Virus 1 Capsid (HIV-1 p24))

Reactivity: Human Immunodeficiency Virus (HIV)

Host: Mouse

Clonality: Monoclonal

Conjugate: This HIV-1 p24 antibody is conjugated to CF®640R

Application: ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC), Coating (Coat)

Clone: P24-661

Product Details anti-HIV-1 p24 Antibody (CF®640R)

Purpose: Mouse Monoclonal anti-HIV p24 (p24/661), CF640R Conjugate

Characteristics: Human immunodeficiency virus (HIV) is a retrovirus that causes acquired immune deficiency syndrome (AIDS), a condition in humans in which the immune system begins to fail, leading to life-threatening opportunistic infections. HIV mainly infects vital cells in the human immune system such as helper T cells (specifically CD4 T cells), macrophages and dendritic cells. Two species of HIV infect humans: HIV-1 and HIV-2, with HIV-1 being the more virulent strain. The gag gene of human immunodeficiency virus 1 (HIV-1) encodes a precursor protein known as Pr55Gag. The viral protease PR cleaves this precursor to generate p17, p24, p7, and p6 proteins, which are required for virus particle assembly. HIV-1 Gag p24 is a capsid protein that constitutes the core of AIDS virus HIV-1. p6 and p7 are the components of the nucleocapsid, and p17 provides a protective matrix. HIV-1 Gag p24 is indispensable to the reproduction of AIDS virus and constitutes an essential element for the AIDS virus particle construction. As this protein is detectable from the early stage of AIDS virus infection, its measurement is commonly used as an indicator of HIV-1 infection and viral load. Primary antibodies are available purified, or with a selection of fluorescent CF® dyes and other labels. CF® dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Immunogen: Recombinant HIV-1 Gag p24 protein

Isotype: IgG1 kappa

Application Details

Application Notes: Immunocytochemistry Acetone or paraformaldehyde fixed 0.5-1 μg/mL

• Immunofluorescence 0.5-1 μg/mL
• ELISA For coating, order Ab without BSA
• Optimal dilution for a specific application should be determined by user

Comment:

HIV-1 infected cells or tissues.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 100 μg/mL

Buffer: PBS/0.1 % BSA/0.05 % azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Protect from light

Target Details for HIV-1 p24

Target: HIV-1 p24 (Human Immunodeficiency Virus 1 Capsid (HIV-1 p24))

Alternative Name: HIV p24

Target Type: Viral Protein

Background: Capsid protein p24, Human immunodeficiency virus type 1 p24, HIV1gp1, HIV-1 Gag p24

Molecular Weight: 24 kDa (mature), 55 kDa & 41 kDa (precursors)

Gene ID: 155348