Kallikrein 1 antibody (AA 25-262)

Catalog No. ABIN6218920

This Rabbit Polyclonal antibody specifically detects Kallikrein 1 in WB and IHC. It exhibits reactivity toward Human.

Quick Overview for Kallikrein 1 antibody (AA 25-262) (ABIN6218920)

Target: Kallikrein 1 (KLK1)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Kallikrein 1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-Kallikrein 1 Antibody

Binding Specificity: AA 25-262

Sequence: IVGGWECEQH SQPWQAALYH FSTFQCGGIL VHRQWVLTAA HCISDNYQLW LGRHNLFDDE NTAQFVHVSE SFPHPGFNMS LLENHTRQAD EDYSHDLMLL RLTEPADTIT DAVKVVELPT EEPEVGSTCL ASGWGSIEPE NFSFPDDLQC VDLKILPNDE CKKAHVQKVT DFMLCVGHLE GGKDTCVGDS GGPLMCDGVL QGVTSWGYVP CGTPNKPSVA VRVLSYVKWI EDTIAENS

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 25-262 of human KLK1 (NP_002248.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IHC,1:50 - 1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid freeze / thaw cycles

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for Kallikrein 1

Target: Kallikrein 1 (KLK1)

Alternative Name: KLK1

Background: Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. This protein is functionally conserved in its capacity to release the vasoactive peptide, Lys-bradykinin, from low molecular weight kininogen.,KLK1,KLKR,Klk6,hK1,Cancer,Invasion and Metastasis,Signal Transduction,Cell Biology & Developmental Biology,Cytoskeleton,Extracellular Matrix,Ubiquitin,Cardiovascular,Angiogenesis,Blood,Coagulation,Serum Proteins,KLK1

Molecular Weight: 23 kDa/28 kDa

Gene ID: 3816

UniProt: P06870

Pathways: Complement System