IGF2R antibody (pSer2409)
Quick Overview for IGF2R antibody (pSer2409) (ABIN6240999)
Target
See all IGF2R AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- pSer2409
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Immunogen
- synthetic peptide
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Application Notes
- WB: 1:1000. IHC: 1:50~100
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Restrictions
- For Research Use only
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Format
- Liquid
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Storage
- 4 °C,-20 °C
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- IGF2R (Insulin-Like Growth Factor 2 Receptor (IGF2R))
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Alternative Name
- IGF2R
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Background
- Transport of phosphorylated lysosomal enzymes from the Golgi complex and the cell surface to lysosomes. Lysosomal enzymes bearing phosphomannosyl residues bind specifically to mannose-6- phosphate receptors in the Golgi apparatus and the resulting receptor-ligand complex is transported to an acidic prelyosomal compartment where the low pH mediates the dissociation of the complex. This receptor also binds IGF2. Acts as a positive regulator of T-cell coactivation, by binding DPP4.
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UniProt
- P11717
Target
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