SUZ12 antibody (AA 496-530)
Quick Overview for SUZ12 antibody (AA 496-530) (ABIN6242140)
Target
See all SUZ12 AntibodiesReactivity
Host
Clonality
Conjugate
Application
Clone
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Binding Specificity
- AA 496-530
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Predicted Reactivity
- H
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Immunogen
- This Mouse Suz12 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 496-530 amino acids from the Central region of Mouse Suz12.
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Isotype
- Ig Fraction
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Application Notes
- WB: 1:1000
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Restrictions
- For Research Use only
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Format
- Liquid
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Storage
- 4 °C,-20 °C
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Expiry Date
- 6 months
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- SUZ12 (SUZ12 Polycomb Repressive Complex 2 Subunit (SUZ12))
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Alternative Name
- Suz12
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Background
- Polycomb group (PcG) protein. Component of the PRC2/EED- EZH2 complex, which methylates 'Lys-9' (H3K9me) and 'Lys-27' (H3K27me) of histone H3, leading to transcriptional repression of the affected target gene. The PRC2/EED-EZH2 complex may also serve as a recruiting platform for DNA methyltransferases, thereby linking two epigenetic repression systems (By similarity). Genes repressed by the PRC2/EED-EZH2 complex include HOXA7, HOXB6 and HOXC8.
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Molecular Weight
- 83026
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UniProt
- Q80U70
Target
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