CD59 antibody (AA 74-110)
Quick Overview for CD59 antibody (AA 74-110) (ABIN6242239)
Target
See all CD59 AntibodiesReactivity
Host
Clonality
Conjugate
Application
Clone
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Binding Specificity
- AA 74-110
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Purification
- This antibody is purified through a protein A column, followed by peptide affinity purification.
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Immunogen
- This CD59 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 74-110 amino acids from the Central region of human CD59.
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Isotype
- Ig Fraction
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Application Notes
- IF: 1:25. WB: 1:2000. IHC-P-Leica: 1:1000. IHC: 1:250. FC: 1:25
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- 4 °C,-20 °C
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Expiry Date
- 6 months
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- CD59
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Alternative Name
- CD59
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Background
- Potent inhibitor of the complement membrane attack complex (MAC) action. Acts by binding to the C8 and/or C9 complements of the assembling MAC, thereby preventing incorporation of the multiple copies of C9 required for complete formation of the osmolytic pore. This inhibitor appears to be species-specific. Involved in signal transduction for T-cell activation complexed to a protein tyrosine kinase.
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Molecular Weight
- 14177
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UniProt
- P13987
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Pathways
- Complement System
Target
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