Calnexin antibody (AA 560-592)

Catalog No. ABIN6242256

The Rabbit Polyclonal anti-Calnexin antibody is suitable to detect Calnexin in samples from Human, Mouse and Rat. It has been validated for WB, FACS and IHC (p).

Quick Overview for Calnexin antibody (AA 560-592) (ABIN6242256)

Target: Calnexin (CANX)

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Calnexin antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: RB56768

Product Details anti-Calnexin Antibody

Binding Specificity: AA 560-592

Predicted Reactivity: M, Rat

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This CANX antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 560-592 amino acids from human CANX.

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:2000. IHC-P: 1:25. FC: 1:25

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Expiry Date: 6 months

Target Details for Calnexin

Target: Calnexin (CANX)

Alternative Name: CANX

Background: Calcium-binding protein that interacts with newly synthesized glycoproteins in the endoplasmic reticulum. It may act in assisting protein assembly and/or in the retention within the ER of unassembled protein subunits. It seems to play a major role in the quality control apparatus of the ER by the retention of incorrectly folded proteins. Associated with partial T-cell antigen receptor complexes that escape the ER of immature thymocytes, it may function as a signaling complex regulating thymocyte maturation. Additionally it may play a role in receptor- mediated endocytosis at the synapse.

Molecular Weight: 67568

UniProt: P27824

Pathways: MAPK Signaling, Thyroid Hormone Synthesis