INTS6 antibody (AA 135-167)

Catalog No. ABIN6242275

Product Details anti-INTS6 Antibody

Target: INTS6 (Integrator Complex Subunit 6 (INTS6))

Binding Specificity: AA 135-167

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This INTS6 antibody is un-conjugated

Application: Western Blotting (WB)

Predicted Reactivity: X, M, Zf

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This INTS6 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 135-167 amino acids from human INTS6.

Clone: RB54384

Isotype: IgG1 kappa

Application Details

Application Notes: WB: 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Expiry Date: 6 months

Target Details for INTS6

Target: INTS6 (Integrator Complex Subunit 6 (INTS6))

Alternative Name: INTS6 (INTS6 Products)

Synonyms: DBI-1 antibody, DDX26 antibody, DDX26A antibody, DICE1 antibody, HDB antibody, INT6 antibody, Notchl2 antibody, EIF3-P48 antibody, EIF3S6 antibody, eIF3-p46 antibody, 2900075H24Rik antibody, AI480962 antibody, Ddx26 antibody, Notch2l antibody, LRRGT00024 antibody, ints6 antibody, zgc:63527 antibody, INTS6 antibody, ints6-b antibody, Int6-A antibody, dbi-1 antibody, ddx26 antibody, ddx26a antibody, dice1 antibody, hdb antibody, int6 antibody, ints6-a antibody, notchl2 antibody, integrator complex subunit 6 antibody, eukaryotic translation initiation factor 3 subunit E antibody, integrator complex subunit 6 like antibody, integrator complex subunit 6 S homeolog antibody, integrator complex subunit 6 L homeolog antibody, INTS6 antibody, EIF3E antibody, Ints6 antibody, ints6l antibody, ints6 antibody, ints6.S antibody, Tsp_09465 antibody, LOC100164318 antibody, ints6.L antibody

Background: Component of the Integrator complex, a complex involved in the small nuclear RNAs (snRNA) U1 and U2 transcription and in their 3'-box-dependent processing. The Integrator complex is associated with the C-terminal domain (CTD) of RNA polymerase II largest subunit (POLR2A) and is recruited to the U1 and U2 snRNAs genes. May have a tumor suppressor role, an ectopic expression suppressing tumor cell growth.

Molecular Weight: 100390

UniProt: Q9UL03