Gelsolin antibody (C-Term)

Catalog No. ABIN6242367

The Rabbit Polyclonal anti-Gelsolin antibody is suitable to detect Gelsolin in samples from Human and Mouse. It has been validated for WB, FACS and IHC (p).

Quick Overview for Gelsolin antibody (C-Term) (ABIN6242367)

Target: Gelsolin (GSN)

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Gelsolin antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: RB18722

Product Details anti-Gelsolin Antibody

Binding Specificity: AA 714-743, C-Term

Predicted Reactivity: B, Pig, Rat

Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogen: This GSN antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 714-743 amino acids from the C-terminal region of human GSN.

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000-1:2000. IHC-P: 1:50~100. FC: 1:10~50

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Expiry Date: 6 months

Target Details for Gelsolin

Target: Gelsolin (GSN)

Alternative Name: GSN

Background: GSN binds to the 'plus' ends of actin monomers and filaments to prevent monomer exchange. The calcium-regulated protein functions in both assembly and disassembly of actin filaments. Defects in this protein are a cause of familial amyloidosis Finnish type (FAF).

Molecular Weight: 85698

NCBI Accession: NP_000168, NP_001121134, NP_001121135, NP_001121136, NP_001121137, NP_001121138, NP_001121139, NP_001244958, NP_001244959, NP_937895

UniProt: P06396

Pathways: Caspase Cascade in Apoptosis, Regulation of Actin Filament Polymerization, Autophagy