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Klotho antibody (C-Term)

KL Reactivity: Human WB Host: Rabbit Polyclonal RB55296 unconjugated
Catalog No. ABIN6242420
  • Target See all Klotho (KL) Antibodies
    Klotho (KL)
    Binding Specificity
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 284-315, C-Term
    Reactivity
    • 31
    • 29
    • 13
    • 7
    • 6
    • 6
    • 5
    • 5
    • 4
    • 3
    • 3
    • 2
    • 1
    Human
    Host
    • 41
    • 4
    • 2
    • 1
    Rabbit
    Clonality
    • 35
    • 13
    Polyclonal
    Conjugate
    • 29
    • 7
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Klotho antibody is un-conjugated
    Application
    • 34
    • 22
    • 12
    • 9
    • 7
    • 5
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Purification
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    Immunogen
    This Klotho antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 284-315 amino acids from the C-terminal region of human Klotho.
    Clone
    RB55296
    Isotype
    Ig Fraction
    Top Product
    Discover our top product KL Primary Antibody
  • Application Notes
    WB: 1:2000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Expiry Date
    6 months
  • Target
    Klotho (KL)
    Alternative Name
    Klotho (KL Products)
    Background
    May have weak glycosidase activity towards glucuronylated steroids. However, it lacks essential active site Glu residues at positions 239 and 872, suggesting it may be inactive as a glycosidase in vivo. May be involved in the regulation of calcium and phosphorus homeostasis by inhibiting the synthesis of active vitamin D (By similarity). Essential factor for the specific interaction between FGF23 and FGFR1 (By similarity).
    Molecular Weight
    116181
    UniProt
    Q9UEF7
    Pathways
    Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Hormone Activity, Growth Factor Binding
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