Klotho antibody (C-Term)
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- Target See all Klotho (KL) Antibodies
- Klotho (KL)
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Binding Specificity
- AA 284-315, C-Term
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This Klotho antibody is un-conjugated
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Application
- Western Blotting (WB)
- Purification
- This antibody is purified through a protein A column, followed by peptide affinity purification.
- Immunogen
- This Klotho antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 284-315 amino acids from the C-terminal region of human Klotho.
- Clone
- RB55296
- Isotype
- Ig Fraction
- Top Product
- Discover our top product KL Primary Antibody
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- Application Notes
- WB: 1:2000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C,-20 °C
- Expiry Date
- 6 months
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- Target
- Klotho (KL)
- Alternative Name
- Klotho (KL Products)
- Background
- May have weak glycosidase activity towards glucuronylated steroids. However, it lacks essential active site Glu residues at positions 239 and 872, suggesting it may be inactive as a glycosidase in vivo. May be involved in the regulation of calcium and phosphorus homeostasis by inhibiting the synthesis of active vitamin D (By similarity). Essential factor for the specific interaction between FGF23 and FGFR1 (By similarity).
- Molecular Weight
- 116181
- UniProt
- Q9UEF7
- Pathways
- Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Hormone Activity, Growth Factor Binding
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