MLF1 antibody (AA 91-126)

Catalog No. ABIN6242439

The Rabbit Polyclonal anti-MLF1 antibody has been validated for WB. It is suitable to detect MLF1 in samples from Human and Mouse.

Quick Overview for MLF1 antibody (AA 91-126) (ABIN6242439)

Target: MLF1 (Myeloid Leukemia Factor 1 (MLF1))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MLF1 antibody is un-conjugated

Application: Western Blotting (WB)

Clone: RB51172

Product Details anti-MLF1 Antibody

Binding Specificity: AA 91-126

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This (Mouse) Mlf1 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 91-126 amino acids from the Central region of (Mouse) Mlf1.

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Expiry Date: 6 months

Target Details for MLF1

Target: MLF1 (Myeloid Leukemia Factor 1 (MLF1))

Alternative Name: Mlf1

Background: Involved in lineage commitment of primary hemopoietic progenitors by restricting erythroid formation and enhancing myeloid formation. Interferes with erythropoietin-induced erythroid terminal differentiation by preventing cells from exiting the cell cycle through suppression of CDKN1B/p27Kip1 levels. Suppresses RFWD2/COP1 activity via CSN3 which activates p53 and induces cell cycle arrest. Binds DNA and affects the expression of a number of genes so may function as a transcription factor in the nucleus.

Molecular Weight: 30432

UniProt: Q9QWV4