MLH1 antibody (C-Term)

Catalog No. ABIN6242443

This anti-MLH1 antibody is a Rabbit Polyclonal antibody detecting MLH1 in WB. Suitable for Human.

Quick Overview for MLH1 antibody (C-Term) (ABIN6242443)

Target: MLH1 (MutL Homolog 1 (MLH1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MLH1 antibody is un-conjugated

Application: Western Blotting (WB)

Clone: RB18204

Product Details anti-MLH1 Antibody

Binding Specificity: C-Term

Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogen: This MLH1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the C-term region of human MLH1.

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Expiry Date: 6 months

Target Details for MLH1

Target: MLH1 (MutL Homolog 1 (MLH1))

Alternative Name: MLH1

Background: MLH1 was identified as a locus frequently mutated in hereditary nonpolyposis colon cancer (HNPCC). The protein is a human homolog of the E. coli DNA mismatch repair gene mutL, consistent with the characteristic alterations in microsatellite sequences (RER+ phenotype) found in HNPCC.

Molecular Weight: 84601

NCBI Accession: NP_000240, NP_001161089, NP_001161090, NP_001161091, NP_001245200, NP_001245202, NP_001245203

UniProt: P40692

Pathways: DNA Damage Repair, Production of Molecular Mediator of Immune Response