PTGDS antibody (C-Term)
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- Target See all PTGDS Antibodies
- PTGDS (Prostaglandin D2 Synthase (PTGDS))
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Binding Specificity
- AA 149-182, C-Term
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Reactivity
- Mouse
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This PTGDS antibody is un-conjugated
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Application
- Western Blotting (WB)
- Purification
- This antibody is purified through a protein A column, followed by peptide affinity purification.
- Immunogen
- This PTGDS antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 149-182 amino acids from the C-terminal region of human PTGDS.
- Clone
- RB47844
- Isotype
- Ig Fraction
- Top Product
- Discover our top product PTGDS Primary Antibody
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- Application Notes
- WB: 1:1000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C,-20 °C
- Expiry Date
- 6 months
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- Target
- PTGDS (Prostaglandin D2 Synthase (PTGDS))
- Alternative Name
- PTGDS (PTGDS Products)
- Background
- Catalyzes the conversion of PGH2 to PGD2, a prostaglandin involved in smooth muscle contraction/relaxation and a potent inhibitor of platelet aggregation. Involved in a variety of CNS functions, such as sedation, NREM sleep and PGE2-induced allodynia, and may have an anti-apoptotic role in oligodendrocytes. Binds small non-substrate lipophilic molecules, including biliverdin, bilirubin, retinal, retinoic acid and thyroid hormone, and may act as a scavenger for harmful hydrophopic molecules and as a secretory retinoid and thyroid hormone transporter. Possibly involved in development and maintenance of the blood-brain, blood-retina, blood-aqueous humor and blood-testis barrier. It is likely to play important roles in both maturation and maintenance of the central nervous system and male reproductive system.
- Molecular Weight
- 21029
- UniProt
- P41222
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