Myocardin antibody (C-Term)

Catalog No. ABIN6242477

This Rabbit Polyclonal antibody specifically detects Myocardin in WB. It exhibits reactivity toward Mouse.

Quick Overview for Myocardin antibody (C-Term) (ABIN6242477)

Target: Myocardin (MYOCD)

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Myocardin antibody is un-conjugated

Application: Western Blotting (WB)

Clone: RB51044

Product Details anti-Myocardin Antibody

Binding Specificity: AA 743-777, C-Term

Predicted Reactivity: H, Pig, Rat

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This Mouse Myocd antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 743-777 amino acids from the C-terminal region of Mouse Myocd.

Isotype: IgG

Application Details

Application Notes: WB: 1:2000. WB: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Expiry Date: 6 months

Target Details for Myocardin

Target: Myocardin (MYOCD)

Alternative Name: Myocd

Background: Smooth muscle cells (SM) and cardiac muscle cells- specific transcriptional factor which uses the canonical single or multiple CArG boxes DNA sequence. Acts as a cofactor of serum response factor (SRF) with the potential to modulate SRF-target genes. Plays a crucial role in cardiogenesis and differentiation of the smooth muscle cell lineage (myogenesis). Isoform 1 mediates the cardiac transcription factor MEF2C-dependent transcription. Isoform 1 and isoform 3 are more active than isoform 2 and isoform 4 in stimulating cardiac muscle promoters.

Molecular Weight: 101400

UniProt: Q8VIM5

Pathways: Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development