Myocardin antibody (Internal Region)

Catalog No. ABIN6257358

The Rabbit Polyclonal anti-Myocardin antibody is suitable to detect Myocardin in samples from Human, Mouse and Rat. It has been validated for WB, IHC, ICC and IF.

Quick Overview for Myocardin antibody (Internal Region) (ABIN6257358)

Target: Myocardin (MYOCD)

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Myocardin antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunofluorescence (IF)

Product Details anti-Myocardin Antibody

Binding Specificity: Internal Region

Purpose: MYOCD Antibody

Specificity: MYOCD Antibody detects endogenous levels of total MYOCD.

Predicted Reactivity: Bovine,Horse,Rabbit,Dog,Chicken,Xenopus

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human MYOCD, corresponding to a region within the internal amino acids.

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C. Stable for 12 months from date of receipt.

Expiry Date: 12 months

Target Details for Myocardin

Target: Myocardin (MYOCD)

Alternative Name: MYOCD

Background:

Description: Smooth muscle cells (SM) and cardiac muscle cells-specific transcriptional factor which uses the canonical single or multiple CArG boxes DNA sequence. Acts as a cofactor of serum response factor (SRF) with the potential to modulate SRF-target genes. Plays a crucial role in cardiogenesis and differentiation of the smooth muscle cell lineage (myogenesis) (By similarity).

Gene: MYOCD

Molecular Weight: 100 kDa

Gene ID: 93649

UniProt: Q8IZQ8

Pathways: Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development