ZKSCAN3 antibody (AA 100-130)

Catalog No. ABIN6242712

The Rabbit Polyclonal anti-ZKSCAN3 antibody is suitable to detect ZKSCAN3 in samples from Human. It has been validated for WB.

Quick Overview for ZKSCAN3 antibody (AA 100-130) (ABIN6242712)

Target: ZKSCAN3 (Zinc Finger Protein 306 (ZKSCAN3))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ZKSCAN3 antibody is un-conjugated

Application: Western Blotting (WB)

Clone: RB53917

Product Details anti-ZKSCAN3 Antibody

Binding Specificity: AA 100-130

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This ZKSCAN3 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 100-130 amino acids from human ZKSCAN3.

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Expiry Date: 6 months

Target Details for ZKSCAN3

Target: ZKSCAN3 (Zinc Finger Protein 306 (ZKSCAN3))

Alternative Name: ZKSCAN3

Background: Transcriptional factor that binds to the consensus sequence 5'-[GT][AG][AGT]GGGG-3' and acts as a repressor of autophagy. Specifically represses expression of genes involved in autophagy and lysosome biogenesis/function such as MAP1LC3B, ULK1 or WIPI2. Associates with chromatin at the ITGB4 and VEGF promoters. Also acts as a transcription activator and promotes cancer cell progression and/or migation in various tumors and myelomas.

Molecular Weight: 60641

UniProt: Q9BRR0