Phone:
+1 877 302 8632
Fax:
+1 888 205 9894 (Toll-free)
E-Mail:
orders@antibodies-online.com

IGF1R antibody (C-Term)

This anti-IGF1R antibody is a Rabbit Polyclonal antibody detecting IGF1R in WB and IHC (p). Suitable for Human, Mouse and Rat.
Catalog No. ABIN6242851

Quick Overview for IGF1R antibody (C-Term) (ABIN6242851)

Target

See all IGF1R Antibodies
IGF1R (Insulin-Like Growth Factor 1 Receptor (IGF1R))

Reactivity

  • 194
  • 109
  • 93
  • 16
  • 8
  • 8
  • 7
  • 3
  • 3
  • 3
  • 2
  • 2
  • 2
  • 1
  • 1
Human, Mouse, Rat

Host

  • 180
  • 34
  • 2
  • 2
  • 1
Rabbit

Clonality

  • 179
  • 38
  • 1
Polyclonal

Conjugate

  • 138
  • 8
  • 8
  • 8
  • 4
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 2
This IGF1R antibody is un-conjugated

Application

  • 141
  • 76
  • 70
  • 63
  • 31
  • 28
  • 28
  • 19
  • 13
  • 13
  • 5
  • 4
  • 4
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone

RB01458
  • Binding Specificity

    • 23
    • 23
    • 19
    • 14
    • 12
    • 12
    • 11
    • 10
    • 6
    • 6
    • 6
    • 6
    • 5
    • 5
    • 5
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1335-1366, C-Term

    Predicted Reactivity

    B

    Purification

    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

    Immunogen

    This IGF1 Receptor (IGF1R) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1335-1366 amino acids from the C-terminal region of human IGF1 Receptor (IGF1R).

    Isotype

    Ig Fraction
  • Application Notes

    WB: 1:2000. WB: 1:2000. WB: 1:1000. IHC-P: 1:50~100

    Restrictions

    For Research Use only
  • Format

    Liquid

    Buffer

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    Preservative

    Sodium azide

    Precaution of Use

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Storage

    4 °C,-20 °C

    Expiry Date

    6 months
  • Target

    IGF1R (Insulin-Like Growth Factor 1 Receptor (IGF1R))

    Alternative Name

    IGF1 Receptor (IGF1R)

    Background

    The IGF1R receptor binds insulin-like growth factor with a high affinity and plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival. The protein possess tyrosine kinase activity.

    Molecular Weight

    154793

    NCBI Accession

    NP_000866

    UniProt

    P08069

    Pathways

    RTK Signaling, Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process, Autophagy
You are here:
Chat with us!