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IGF1R antibody (C-Term)

Name: IGF1R antibody (C-Term)
SKU: ABIN6242851
Price: 451 USD
Availability: InStock

IGF1R Reactivity: Human, Mouse, Rat WB, IHC (p) Host: Rabbit Polyclonal RB01458 unconjugated

All lanes : Anti-IGF1 Receptor (IGF1R) Antibody (C-term) at 1:2000 dilution Lane 1: A431 whole cell lysate Lane 2: Hela whole cell lysate Lysates/proteins at 20 μg per lane. (IGF1R antibody (C-Term))

Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. (IGF1R antibody (C-Term))

IHC (p)

All lanes : Anti-IGF1 Receptor (IGF1R) Antibody (C-term) at 1:2000 dilution Lane 1: 293T/17 whole cell lysate Lane 2: A431 whole cell lysate Lane 3: C2C12 whole cell lysate Lane 4: C6 whole cell lysate Lane 5: Hela whole cell lysate Lane 6: NIH/3T3 whole cell lysate Lysates/proteins at 20 μg per lane. (IGF1R antibody (C-Term))

Western blot analysis of anti-IGF1R Pab (ABIN6242851 and ABIN6579005) in SK-BR-3 cell lysate. (IGF1R antibody (C-Term))

4 images

Catalog No. ABIN6242851

Datasheet as PDF

Target See all IGF1R Antibodies

IGF1R (Insulin-Like Growth Factor 1 Receptor (IGF1R))
Binding Specificity
23

23

19

14

12

12

11

10

6

6

6

5

5

5

4

4

4

4

4

4

3

3

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
AA 1335-1366, C-Term
Reactivity
187

108

92

16

8

8

7

3

3

2

2

2

1

1

1
Human, Mouse, Rat
Host
172

29

2

1

1
Rabbit
Compatible Secondaries
Clonality
174

31
Polyclonal
Conjugate
126

8

8

7

4

3

3

3

3

3

3

3

3

3

3

3

3

3

3

3

3

3

2
This IGF1R antibody is un-conjugated
Application
131

72

61

60

32

25

18

13

13

11

5

4

4

3

2

1

1

1

1

1

1
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Predicted Reactivity

B

Purification

This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogen

This IGF1 Receptor (IGF1R) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1335-1366 amino acids from the C-terminal region of human IGF1 Receptor (IGF1R).

Clone

RB01458

Isotype

Ig Fraction

Top Product

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anti-Insulin-Like Growth Factor 1 Receptor (IGF1R) (AA 251-350) antibody
IGF1R Reactivity: Human, Mouse, Rat, Dog FACS Host: Rabbit Polyclonal unconjugated

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IGF1R Reactivity: Human, Mouse, Rat WB, IHC, ELISA, IF, ICC Host: Rabbit Polyclonal unconjugated

anti-Insulin-Like Growth Factor 1 Receptor (IGF1R) (pTyr1165), (pTyr1166) antibody
IGF1R Reactivity: Human, Mouse, Rat WB, IHC, ELISA, IF, ICC Host: Rabbit Polyclonal unconjugated

anti-Insulin-Like Growth Factor 1 Receptor (IGF1R) (pTyr1161) antibody
IGF1R Reactivity: Human, Mouse, Rat WB, IHC, ELISA, IF, IP, ICC Host: Rabbit Polyclonal unconjugated

anti-Insulin-Like Growth Factor 1 Receptor (IGF1R) (AA 51-77) antibody
IGF1R Reactivity: Human WB, IHC, ELISA, IF, FACS Host: Rabbit Polyclonal unconjugated

anti-Insulin-Like Growth Factor 1 Receptor (IGF1R) (C-Term) antibody
IGF1R Reactivity: Human, Mouse, Rat WB, IHC, ELISA, IF, ICC Host: Rabbit Polyclonal unconjugated

anti-Insulin-Like Growth Factor 1 Receptor (IGF1R) (AA 51-77), (N-Term) antibody
IGF1R Reactivity: Human WB, IF, FACS, IHC (p) Host: Rabbit Polyclonal RB15292 unconjugated

anti-Insulin-Like Growth Factor 1 Receptor (IGF1R) (AA 660-760) antibody
IGF1R Reactivity: Human WB Host: Rabbit Polyclonal unconjugated

anti-Insulin-Like Growth Factor 1 Receptor (IGF1R) (AA 763-955) antibody
IGF1R Reactivity: Human WB, IHC, IP, ICC Host: Rabbit Polyclonal unconjugated

anti-Insulin-Like Growth Factor 1 Receptor (IGF1R) (Tyr1346) antibody
IGF1R Reactivity: Human WB, IHC, ELISA Host: Rabbit Polyclonal unconjugated

Application Notes

WB: 1:2000. WB: 1:2000. WB: 1:1000. IHC-P: 1:50~100

Restrictions

For Research Use only
Format

Liquid

Buffer

Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative

Sodium azide

Precaution of Use

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage

4 °C,-20 °C

Expiry Date

6 months
Target

IGF1R (Insulin-Like Growth Factor 1 Receptor (IGF1R))

Alternative Name

IGF1 Receptor (IGF1R) (IGF1R Products)

Background

The IGF1R receptor binds insulin-like growth factor with a high affinity and plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival. The protein possess tyrosine kinase activity.

Molecular Weight

154793

NCBI Accession

NP_000866

UniProt

P08069

Pathways

RTK Signaling, Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process, Autophagy