Rabenosyn 5 antibody (AA 41-65)

Catalog No. ABIN6242883

The Rabbit Polyclonal anti-Rabenosyn 5 antibody is suitable to detect Rabenosyn 5 in samples from Human. It has been validated for WB.

Quick Overview for Rabenosyn 5 antibody (AA 41-65) (ABIN6242883)

Target: Rabenosyn 5 (ZFYVE20) (Zinc Finger, FYVE Domain Containing 20 (ZFYVE20))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Rabenosyn 5 antibody is un-conjugated

Application: Western Blotting (WB)

Clone: RB52910

Product Details anti-Rabenosyn 5 Antibody

Binding Specificity: AA 41-65

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This ZFYVE20 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 41-65 amino acids from the human region of human ZFYVE20.

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:8000. WB: 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Expiry Date: 6 months

Target Details for Rabenosyn 5

Target: Rabenosyn 5 (ZFYVE20) (Zinc Finger, FYVE Domain Containing 20 (ZFYVE20))

Alternative Name: ZFYVE20

Background: Rab4/Rab5 effector protein acting in early endocytic membrane fusion and membrane trafficking of recycling endosomes. Required for endosome fusion either homotypically or with clathrin coated vesicles. Plays a role in the lysosomal trafficking of CTSD/cathepsin D from the Golgi to lysosomes. Also promotes the recycling of transferrin directly from early endosomes to the plasma membrane. Binds phospholipid vesicles containing phosphatidylinositol 3-phosphate (PtdInsP3) (PubMed:< a href="http://www.uniprot.org/citations/11062261" target="_blank">11062261, PubMed:< a href="http://www.uniprot.org/citations/11788822" target="_blank">11788822, PubMed:< a href="http://www.uniprot.org/citations/15020713" target="_blank">15020713). Plays a role in the recycling of transferrin receptor to the plasma membrane (PubMed:< a href="http://www.uniprot.org/citations/22308388" target="_blank">22308388).

Molecular Weight: 88870

UniProt: Q9H1K0

Pathways: Toll-Like Receptors Cascades