UBE2C antibody (C-Term)

Catalog No. ABIN6243143

This Mouse Monoclonal antibody specifically detects UBE2C in WB. It exhibits reactivity toward Human.

Quick Overview for UBE2C antibody (C-Term) (ABIN6243143)

Target: UBE2C (Ubiquitin-Conjugating Enzyme E2C (UBE2C))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This UBE2C antibody is un-conjugated

Application: Western Blotting (WB)

Clone: 2001CT211-37-61

Product Details anti-UBE2C Antibody

Binding Specificity: C-Term

Predicted Reactivity: B, Pr, M

Purification: This antibody is purified through a protein G column, followed by dialysis against PBS.

Immunogen: This UBE2C antibody is generated from a mouse immunized with a KLH conjugated synthetic peptide between 137~172 amino acids from the C-terminal region of human UBE2C.

Isotype: IgG1 kappa

Application Details

Application Notes: WB: 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified monoclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Expiry Date: 6 months

Target Details for UBE2C

Target: UBE2C (Ubiquitin-Conjugating Enzyme E2C (UBE2C))

Alternative Name: UBE2C

Background: Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In vitro catalyzes 'Lys- 11'- and 'Lys-48'-linked polyubiquitination. Acts as an essential factor of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated ubiquitin ligase that controls progression through mitosis. Acts by initiating 'Lys-11'-linked polyubiquitin chains on APC/C substrates, leading to the degradation of APC/C substrates by the proteasome and promoting mitotic exit.

Molecular Weight: 19652

UniProt: O00762

Pathways: Ubiquitin Proteasome Pathway