TNRC6A antibody (AA 855-885)
Quick Overview for TNRC6A antibody (AA 855-885) (ABIN6243375)
Target
Reactivity
Host
Clonality
Application
Clone
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Binding Specificity
- AA 855-885
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Purification
- This antibody is purified through a protein A column, followed by peptide affinity purification.
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Immunogen
- This TNRC6A antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 855-885 amino acids from the Central region of human TNRC6A.
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Isotype
- Ig Fraction
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Application Notes
- WB: 1:1000-1:2000
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- 4 °C,-20 °C
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Expiry Date
- 6 months
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- TNRC6A (Trinucleotide Repeat Containing 6A (TNRC6A))
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Alternative Name
- TNRC6A
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Background
- Plays a role in RNA-mediated gene silencing by both micro-RNAs (miRNAs) and short interfering RNAs (siRNAs). Required for miRNA-dependent repression of translation and for siRNA- dependent endonucleolytic cleavage of complementary mRNAs by argonaute family proteins. As scaffoldng protein associates with argonaute proteins bound to partially complementary mRNAs and simultaneously can recruit CCR4-NOT and PAN deadenylase complexes.
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Molecular Weight
- 210297
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UniProt
- Q8NDV7
Target
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