APIP antibody (AA 111-142)

Catalog No. ABIN6243533

This Rabbit Polyclonal antibody specifically detects APIP in WB and IHC (p). It exhibits reactivity toward Human.

Quick Overview for APIP antibody (AA 111-142) (ABIN6243533)

Target: APIP (APAF1 Interacting Protein (APIP))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This APIP antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: RB55049

Product Details anti-APIP Antibody

Binding Specificity: AA 111-142

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This APIP antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 111-142 amino acids from the Central region of human APIP.

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:2000. IHC-P: 1:25

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Expiry Date: 6 months

Target Details for APIP

Target: APIP (APAF1 Interacting Protein (APIP))

Alternative Name: APIP

Background: Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P). Functions in the methionine salvage pathway, which plays a key role in cancer, apoptosis, microbial proliferation and inflammation. May inhibit the CASP1-related inflammatory response (pyroptosis), the CASP9-dependent apoptotic pathway and the cytochrome c-dependent and APAF1-mediated cell death.

Molecular Weight: 27125

UniProt: Q96GX9

Pathways: Methionine Biosynthetic Process